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Products_type
Antibody
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Products_short_name
[LF / LTF / Lactoferrin]
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Products_name_syn
[Anti-LF / LTF / Lactoferrin Antibody (clone 1A1) IHC-plus; LTF; GIG12; Growth-inhibiting protein 12; HLF2; Lactotransferrin; Lactoferrin; LF; Neutrophil lactoferrin; Talalactoferrin; Human LF; LTF; Lactoferrin]
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Other_names
[lactotransferrin isoform 1; Lactotransferrin; lactotransferrin; kaliocin-1; lactoferricin; lactoferroxin; talalactoferrin; neutrophil lactoferrin; growth-inhibiting protein 12; epididymis luminal protein 110; lactotransferrin; Growth-inhibiting protein 12; TalalactoferrinCleaved into the following 5 chains:Lactoferricin-H; Lfcin-H; Kaliocin-1; Lactoferroxin-A; Lactoferroxin-B; Lactoferroxin-C]
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Products_gene_name
[LF]
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Other_gene_names
[LTF; LTF; LF; HLF2; GIG12; HEL110; GIG12; LF; Lactoferrin; Lfcin-H]
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Clonality
Monoclonal
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Clone
[1A1]
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Reactivity
Human
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Specificity
Recognizes human lactoferrin, a 78kD globular protein found in body secretions such as milk and saliva and is a member of the transferrin family proteins. Transferrins control the level of free iron in the body, by binding and transporting iron. Lactoferrin does not appear to have a transporting function, instead it has antimicrobial activity, by keeping the levels of iron in body fluids low and thus preventing microbes from acquiring iron. Removing free iron from body fluids and inflamed areas also serve to protect against the damaging effects of free radicals. Lactoferrin is used as a therapeutic and prophylactic treatment of various illnesses, such as cancers and intestinal illnesses. May be used to detect lactoferrin in ELISA assays.
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Purity
Affinity Purified
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Form
PBS, pH 7.4, 0.09% sodium azide.
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Concentration
1 mg/ml
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Storage_stability
+4 degree C or -20 degree C, Avoid repeated freezing and thawing.
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Tested_application
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
