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Products_type
Antibody
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Products_short_name
[BAFF Receptor]
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Products_name_syn
[Anti-BAFF Receptor Antibody (clone 11C1) IHC-plus; BAFFR; BR3; BAFF receptor; BLyS receptor 3; CD268; CD268 antigen; CVID4; Prolixin; BAFF-R; BROMIX; Human BAFF Receptor]
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Other_names
[tumor necrosis factor receptor superfamily member 13C; Tumor necrosis factor receptor superfamily member 13C; tumor necrosis factor receptor superfamily member 13C; BAFF receptor; BLyS receptor 3; B cell-activating factor receptor; B-cell-activating factor receptor; tumor necrosis factor receptor superfamily, member 13C; B-cell-activating factor receptor; BAFF receptor; BAFF-R; BLyS receptor 3; CD_antigen: CD268]
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Products_gene_name
[TNFRSF13C]
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Other_gene_names
[TNFRSF13C; TNFRSF13C; BAFFR; CD268; CVID4; BAFF-R; BROMIX; prolixin; BAFFR; BR3; BAFF-R]
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Clonality
Monoclonal
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Clone
[11C1]
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Reactivity
Human
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Specificity
BAFF-R-L1.2 transfectants
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Purity
Affinity Purified
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Form
Phosphate-buffered solution, pH 7.2, 0.09% sodium azide.
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Concentration
0.5 mg/ml
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Storage_stability
Store at 4 degree C. Do not freeze.
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Tested_application
Immunohistochemistry (IHC - Paraffin), Flow Cytometry (FC/FACS)
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
