Mouse IgG3-LE/AF

• Catalog number
  MBS679056
• Price
  Please ask
• Size
  0.5 mg

• Products_type
  Isotype Control
• Products_short_name
  [Mouse IgG3 Isotype Control]
• Products_name_syn
  [Mouse IgG3 - Low Endotoxin/Azide-Free; Mouse IgG3 Isotype Control]
• Clonality
  Monoclonal
• Clone
  [B10]
• Specificity
  Unknown
• Form
  Low Endotoxin, Azide - Free (LE/AF)
• Storage_stability
  The purified (UNLB) antibody is supplied as 1.0 mg of purified immunoglobulin in 1.0 mL of 100mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2-8 degree C. The fluorescein (FITC) conjugate is supplied as 100 tests in 1.0 mL PBS/NaN3. Store at 2-8 degree C. The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 degree C. The R-phycoerythrin (R-PE) and allophycocyanin (APC) conjugates are supplied as100 tests in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze! The Spectral Red (SPRD), R-phycoerythrin-Cyanine 5.5 (R-PE-CY 5.5) and R-phycoerythrin-Cyanine 7 (R-PE-CY 7) conjugates are supplied as 100 tests in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze! The low endotoxin, azide-free (LE/AF) antibody is supplied as 0.5 mg purified immunoglobulin in 1.0 mL of PBS. Aliquot and store at or below -20 degree C. With the exception of the low endotoxin, azide-free product, the vials should be stored at 2-8 degree C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Aliquot and freeze the low endotoxin, azide-free product at -20 degree C immediately upon receipt. Each reagent is stable for the period shown on the bottle label if stored as directed.
• Tested_application
  ELISA; Flow Cytometry
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  IgG3-LE/AF  
• Gene symbol
  FUT3, HPS4, NPAS4
• Short name
  Mouse IgG3-LE/AF
• Technique
  Mouse, mouses
• Host
  Mouse
• Isotype
  Mouse IgG3 lambda, IgG3
• Species
  Mouse, Mouses
• Alternative name
  Mouse IgG3-LE/AF
• Alternative technique
  murine

Gene info

• Identity
  HGNC:4014
• Gene
  FUT3
• Long gene name
  fucosyltransferase 3 (Lewis blood group)
• Synonyms gene
  • LE
• Synonyms gene name
  • fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group included)
• Synonyms
  • CD174
• Synonyms name
  • galactoside 3(4)-L-fucosyltransferase
• Locus
  19p13.3
• Discovery year
  1993-04-08
• Entrez gene record
  2525
• Pubmed identfication
  • 1977660
  • 1740457
• RefSeq identity
  • NM_000149
• Classification
  • Fucosyltransferases
  • Blood group antigens
  • CD molecules
• VEGA ID
  OTTHUMG00000180614
• Locus Specific Databases
  • Blood Group Antigen Mutation Database
  • LRG_800

Gene info

• Identity
  HGNC:15844
• Gene
  HPS4
• Long gene name
  HPS4 biogenesis of lysosomal organelles complex 3 subunit 2
• Synonyms gene name
  • Hermansky-Pudlak syndrome 4
• Synonyms
  • KIAA1667
  • LE
  • BLOC3S2
• Locus
  22q12.1
• Discovery year
  2001-06-28
• Entrez gene record
  89781
• Pubmed identfication
  • 11836498
  • 12663659
• RefSeq identity
  • NM_022081
• Classification
  • Biogenesis of lysosomal organelles complex 3
• VEGA ID
  OTTHUMG00000030459
• Locus Specific Databases
  • Mutations of the Human light ear Gene (le, HPS4)
  • LRG_590

Gene info

• Identity
  HGNC:18983
• Gene
  NPAS4
• Long gene name
  neuronal PAS domain protein 4
• Synonyms
  • PASD10
  • NXF
  • Le-PAS
  • bHLHe79
• GenBank acession
  • AB049469
• Locus
  11q13.2
• Discovery year
  2005-09-26
• Entrez gene record
  266743
• Pubmed identfication
  • 14701734
• RefSeq identity
  • NM_178864
• Classification
  • Basic helix-loop-helix proteins
• VEGA ID
  OTTHUMG00000167045

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