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Products_type
Antibody
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Products_short_name
[p21/WAF1/ cip1/Cyclin-dependent kinase inhibitor 1]
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Other_names
[cyclin-dependent kinase inhibitor 1 isoform 1; Cyclin-dependent kinase inhibitor 1; cyclin-dependent kinase inhibitor 1; DNA synthesis inhibitor; CDK-interacting protein 1; CDK-interaction protein 1; wild-type p53-activated fragment 1; melanoma differentiation associated protein 6; cyclin-dependent kinase inhibitor 1A (p21, Cip1); CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6; p21]
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Other_gene_names
[CDKN1A; CDKN1A; P21; CIP1; SDI1; WAF1; CAP20; CDKN1; MDA-6; p21CIP1; CAP20; CDKN1; CIP1; MDA6; PIC1; SDI1; WAF1; MDA-6]
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Clonality
Monoclonal
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Clone
[WA1]
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Reactivity
Human, non human primates
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Specificity
The antibody WA1 is directed against human p21/WAF1, but also recognizes this protein in non-human primates. Reports suggest that this antibody recognizes an epitope within the carboxy-terminal region of p21/WAF1.
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Form
Each vial contains 100 ug 1mg/ml purified monoclonal antibody in PBS containing 0.09% sodium azide.
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Storage_stability
Store at 4 degree C, or in small aliquots at -20 degree C.
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Tested_application
Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC-frozen), Immunohistochemistry (IHC-paraffin), Western Blot, ELISA (EIA)
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
