Mouse Anti-Mouse H-2Kd/H-2Dd-PE
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Catalog number
MBS673687
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Price
Please ask
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Size
5x0.1 mg
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Products_type
Secondary Antibody
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Products_short_name
[Mouse (C3H/HeJ) Anti-Mouse H-2Kd/H-2Dd]
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Products_name_syn
[Mouse Anti-Mouse H-2Kd/H-2Dd - Phycoerythrin-Labeled; Mouse (C3H/HeJ) Anti-Mouse H-2Kd/H-2Dd]
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Clonality
Monoclonal
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Clone
[34-1-2S]
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Reactivity
Mouse
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Specificity
An epitope in the alpha 3 domain that is common to H-2Kd and H-2Dd The "classical" MHC Class I molecules are histocompatibility antigens encoded by the H-2 gene complex and consist of heterodimers of highly polymorphic alpha chains noncovalently associated with the invariant beta 2-microglobulin.3,4 These antigens are expressed on most nucleated cells but expression varies on different cell types. MHC Class I molecules present endogenously synthesized peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells.5 MHC Class I antigens expressed on thymic epithelial cells regulate the positive and negative selection of CD8+ T cells during T cell ontogeny.3,6 The monoclonal antibody 34-1-2S binds to a common determinant in the alpha 3 domains of H-2Kd and H-2Dd in the presence or absence of beta 2 microglobulin.7,8 It cross reacts with the alpha 3 domain of H-2Kb.1,2
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Form
R - phycoerythrin (R - PE) Conjugate
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Storage_stability
The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 degree C. The fluorescein (FITC) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 degree C. The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 degree C. The R-phycoerythrin (R-PE) conjugate is supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze! Protect conjugated forms from light. Each reagent is stable for the period shown on the bottle label if stored as directed.
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Tested_application
Flow Cytometry; Immunohistochemistry (Acetone Fixed/Frozen Sections)
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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Gene target
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Gene symbol
ETV3, ERF
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Short name
Mouse Anti-Mouse H-2Kd/H-2Dd-PE
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Technique
anti-, Mouse, anti, antibody to, antibodies, mouses
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Host
Mouse
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Isotype
Mouse IgG2a kappa
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Label
PE
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Species
Mouse, Mouses
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Alternative name
Mouse Antibody toMouse H-2Kd/H-2Dd-peroxidase
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Alternative technique
murine, antibodies
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Gene info
Gene info
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Identity
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Gene
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Long gene name
ETS2 repressor factor
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Synonyms gene name
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Synonyms
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GenBank acession
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Locus
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Discovery year
1998-07-17
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- ETS transcription factor family
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Electrophoresis in which a second perpendicular electrophoretic transport is performed on the separate components resulting from the first electrophoresis. This technique is usually performed on polyacrylamide gels.
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Tree numbers
- E05.196.401.250
- E05.301.300.230
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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