Mouse Anti-Human TLR6-UNLB

• Catalog number
  MBS670143
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Antibody
• Products_short_name
  [Toll-like Receptor 6 (TLR6)]
• Products_name_syn
  [Mouse Anti-Human TLR6 - Purified, Unlabeled Antibody; Mouse Anti-Human Toll-like Receptor 6 (TLR6)]
• Other_names
  [toll-like receptor 6; Toll-like receptor 6; toll-like receptor 6; OTTHUMP00000218187; toll-like receptor 6]
• Other_gene_names
  [TLR6; CD286]
• Clonality
  Monoclonal
• Clone
  [3B6]
• Reactivity
  Human
• Specificity
  Human Toll-like Receptor 6 (TLR6) The Toll-like receptor (TLR) family is comprised of Type I transmembrane proteins characterized by an extracellular leucine-rich domain and a cytoplasmic tail that contains a conserved region call the Toll/IL-1 (TIR) domain. First discovered in Drosophila, TLRs recognize specific molecular patterns that are present in microbial components and respond to these components in order eliminate or limit invading microbes. To date, ten mammalian homologs of TLRs have been described. TLRs signal through adaptor molecules such as MyD88 leading to NF- kappa B activation, c-Jun N-terminal kinase activation (JNK), cytokine secretion and the inflammatory response. The amino acid sequence of human TLR6 is most similar to hTLR1 with 69% identity. TLR6 recognizes mycoplasmal macrophage-activating lipopeptide- 2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B. burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2.1-6
• Form
  Purified (UNLB) Antibody
• Storage_stability
  The purified antibody (UNLB) is supplied as 0.1 mg purified immunoglobulin in 0.2 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 degree C. Reagents are stable for the period shown on the label if stored as directed.
• Tested_application
  ELISA
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Test
  MyBioSource supplies antibodies that are for research of human proteins. Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Latin name
  Mus musculus

• Gene target
  TLR6-UNLB  
• Gene symbol
  TLR6
• Short name
  Mouse Anti- TLR6-UNLB
• Technique
  anti-Human, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, mouses
• Host
  Mouse
• Isotype
  Mouse IgG2a kappa
• Species
  Human, Humans, Mouses
• Alternative name
  Mouse Antibody toHuman toll-like receptor 6-UNLB
• Alternative technique
  murine, antibodies
• Alternative to gene target
  toll-like receptor 6, CD286, TLR6 and IDBG-13675 and ENSG00000174130 and 10333, lipopeptide binding, Plasma membranes, Tlr6 and IDBG-165921 and ENSMUSG00000051498 and 21899, BT.45021 and IDBG-641606 and ENSBTAG00000014031 and 407237

Gene info

• Identity
  HGNC:16711
• Gene
  TLR6
• Long gene name
  toll like receptor 6
• Synonyms gene name
  • toll-like receptor 6
• Synonyms
  • CD286
• Locus
  4p14
• Discovery year
  2001-10-01
• Entrez gene record
  10333
• Pubmed identfication
  • 10231569
• Classification
  • Toll like receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000128579

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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