MOUSE ANTI HUMAN COLLAGEN I

• Catalog number
  MBS211541
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Antibody
• Products_short_name
  [COLLAGEN I]
• Other_names
  [collagen alpha-2(I) chain; Collagen alpha-2(I) chain; collagen alpha-2(I) chain; collagen alpha-2(I) chain; type I procollagen; alpha 2(I)-collagen; alpha-2 type I collagen; collagen I, alpha-2 polypeptide; collagen of skin, tendon and bone, alpha-2 chain; collagen, type I, alpha 2; Alpha-2 type I collagen]
• Other_gene_names
  [COL1A2; COL1A2; OI4]
• Clonality
  Monoclonal
• Clone
  [NFI/20]
• Reactivity
  Human
• Specificity
  COLLAGEN I This item is specific for human Collagen I and does not recognise Collagen types II, III and IV. Collagen is located in the extracellular matrix of connective tissues. It is part of the interacting network of proteoglycans and proteins that provides a structural framework for both soft and calcified connective tissues. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis.
• Form
  Purified (Ig fraction - lyophilised)
• Storage_stability
  Prior to reconstitution store at +4 degree C. After reconstitution store at -20 degree C. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Shelf Life: 12 months from date of reconstitution.
• Tested_application
  Immunohistology - Frozen (IHC), ELISA (EIA)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Gene
  Collagen Types in bones and muscles can be hydrolyzed and used in human grafts. ( Type II )
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  COLLAGEN  
• Gene symbol
  COL1A2, COL1A1, COL1AR
• Short name
  MOUSE ANTI COLLAGEN I
• Technique
  anti human, Mouse, anti, antibody to, anti human antibodies, mouses
• Host
  Mouse
• Isotype
  IgG1
• Species
  Human, Humans, Mouses
• Alternative name
  MOUSE antibody to H. sapiens COLLAGEN I
• Alternative technique
  murine, antibodies

Gene info

• Identity
  HGNC:2198
• Gene
  COL1A2
• Long gene name
  collagen type I alpha 2 chain
• Synonyms gene
  • OI4
• Synonyms gene name
  • osteogenesis imperfecta type IV
  • collagen, type I, alpha 2
  • collagen type I alpha 2
• Synonyms name
  • alpha 2(I)-collagen
  • alpha-2 collagen type I
  • type I procollagen
  • collagen I, alpha-2 polypeptide
  • collagen of skin, tendon and bone, alpha-2 chain
• GenBank acession
  • Z74616
• Locus
  7q21.3
• Discovery year
  2001-06-22
• Entrez gene record
  1278
• Pubmed identfication
  • 3857213
  • 2897363
• RefSeq identity
  • NM_000089
• Classification
  • Collagens
• VEGA ID
  OTTHUMG00000148675
• Locus Specific Databases
  • Osteogenesis Imperfecta Variant Database
  • LRG_2

Gene info

• Identity
  HGNC:2197
• Gene
  COL1A1
• Long gene name
  collagen type I alpha 1 chain
• Synonyms gene name
  • collagen, type I, alpha 1
• Synonyms
  • OI4
• GenBank acession
  • Z74615
• Locus
  17q21.33
• Discovery year
  2001-06-22
• Entrez gene record
  1277
• Pubmed identfication
  • 3178743
  • 2857713
• RefSeq identity
  • NM_000088
• Classification
  • Collagens
• VEGA ID
  OTTHUMG00000148674
• Locus Specific Databases
  • Osteogenesis Imperfecta Variant Database
  • LRG_1

Gene info

• Identity
  HGNC:2199
• Gene
  COL1AR
• Long gene name
  collagen type I alpha receptor
• Synonyms gene name
  • collagen, type I, alpha, receptor
• Locus
  15
• Discovery year
  1989-05-08
• Entrez gene record
  1279
• Pubmed identfication
  • 2840666

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products