MOUSE ANTI Cdk4

• Catalog number
  MBS212447
• Price
  Please ask
• Size
  5x0.1 mg

• Products_type
  Antibody
• Products_short_name
  [Cdk4]
• Other_names
  [cyclin-dependent kinase 4; Cyclin-dependent kinase 4; cyclin-dependent kinase 4; cell division protein kinase 4; cyclin-dependent kinase 4; Cell division protein kinase 4; PSK-J3]
• Products_gene_name
  [Cdk4]
• Other_gene_names
  [CDK4; CDK4; CMM3; PSK-J3]
• Clonality
  Monoclonal
• Clone
  [DCS-31.2]
• Reactivity
  Reacts with: Mouse, Human, Rat; N.B. Antibody reactivity and working conditions may vary between species.
• Specificity
  Mouse anti CDK4 antibody clone DCS31.2 recognizes cyclin dependent kinase 4 (Cdk4), a ~34 kDa protein involved in the regulation of cell cycle progression between G1 and S. Mouse anti CDK4 antibody clone DCS31.2 does not cross react with other cdk's and does not co-precipitate the D type cyclins bound to cdk4.
• Form
  Purified IgG - liquid
• Concentration
  IgG concentration 0.5 mg/ml
• Storage_stability
  Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
• Tested_application
  Immunohistochemistry-Frozen (IHC-Fr), Immunoprecipitation (IP), Western Blot (WB)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  Cdk4  
• Gene symbol
  CDK4, CDKN2C, CDKN2D
• Short name
  MOUSE ANTI Cdk4
• Technique
  Mouse, anti, antibody to, mouses
• Host
  Mouse
• Isotype
  IgG1
• Species
  Mouse, Mouses
• Alternative name
  MOUSE antibody to cyclin-dependent kinase 4
• Alternative technique
  murine, antibodies
• Alternative to gene target
  cyclin-dependent kinase 4, CMM3 and PSK-J3, CDK4 and IDBG-43642 and ENSG00000135446 and 1019, transferase activity, nuclei, Cdk4 and IDBG-194056 and ENSMUSG00000006728 and 102641469,12567

Gene info

• Identity
  HGNC:1773
• Gene
  CDK4
• Long gene name
  cyclin dependent kinase 4
• Synonyms
  • PSK-J3
• GenBank acession
  • M14505
• Locus
  12q14.1
• Discovery year
  1993-07-28
• Entrez gene record
  1019
• Pubmed identfication
  • 8275715
• RefSeq identity
  • NM_000075
• Classification
  • Cyclin dependent kinases
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000170382
• Locus Specific Databases
  • LRG_490

Gene info

• Identity
  HGNC:1789
• Gene
  CDKN2C
• Long gene name
  cyclin dependent kinase inhibitor 2C
• Synonyms gene name
  • cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
• Synonyms
  • INK4C
  • p18
• GenBank acession
  • BC000598
• Locus
  1p32.3
• Discovery year
  1995-07-06
• Entrez gene record
  1031
• Pubmed identfication
  • 8001816
  • 9636670
• RefSeq identity
  • NM_001262
• Classification
  • Ankyrin repeat domain containing
• VEGA ID
  OTTHUMG00000008046

Gene info

• Identity
  HGNC:1790
• Gene
  CDKN2D
• Long gene name
  cyclin dependent kinase inhibitor 2D
• Synonyms gene name
  • cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
• Synonyms
  • INK4D
  • p19
• Locus
  19p13.2
• Discovery year
  1995-07-06
• Entrez gene record
  1032
• Pubmed identfication
  • 8575754
• RefSeq identity
  • NM_079421
• Classification
  • Ankyrin repeat domain containing
• VEGA ID
  OTTHUMG00000180583

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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