Mouse anti AKR1B1

• Catalog number
  MBS225524
• Price
  Please ask
• Size
  5x0.1 mL

• Products_type
  Antibody
• Products_short_name
  [AKR1B1]
• Products_name_syn
  [AKR1B1 Antibody]
• Other_names
  [Aldose reductase; Aldose reductase; aldose reductase; aldo-keto reductase family 1 member B; Aldehyde reductase; Aldo-keto reductase family 1 member B1]
• Products_gene_name
  [AKR1B1]
• Other_gene_names
  [AKR1B1; AKR1B1; AR; ADR; ALR2; ALDR1; ALDR1; AR]
• Clonality
  Monoclonal
• Clone
  [CPTC28]
• Reactivity
  Reacts with: Mouse, Rat N.B Antibody reactivity and working conditions may vary between species.
• Specificity
  Mouse anti Human AKR1B1 antibody recognizes the aldose reductase, also known as Lii5-2 CTCL tumor antigen, aldehyde reductase 1, aldo-keto reductase family 1 member B1, ADR, or low Km aldose reductase. AKR1B1 gene encodes a member of the aldo/keto reductase super family, which consists of more than 40 known enzymes and proteins. This member catalyes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for AKR1B1. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome informatics database (provided by RefSeq, Feb 2009). Mouse anti Human AKR1B1 antibody detects a band of 36 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
• Purity
  Purified by affinity chromatography on Protein G from tissue culture supernatant
• Form
  Liquid in phosphate buffered saline with 0.09% sodium azide (NaN3).
• Storage_stability
  Store undiluted at -20 degree C. Avoid repeated freeze/thaw cycles.
• Tested_application
  Western Blot (WB)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  AKR1B1  
• Gene symbol
  AKR1B1
• Short name
  Mouse anti AKR1B1
• Technique
  Mouse, anti, antibody to, mouses
• Host
  Mouse
• Isotype
  IgG1
• Species
  Mouse, Mouses
• Alternative name
  Mouse antibody to AKR1B1
• Alternative technique
  murine, antibodies

Gene info

• Identity
  HGNC:381
• Gene
  AKR1B1
• Long gene name
  aldo-keto reductase family 1 member B
• Synonyms gene
  • ALDR1
• Synonyms gene name
  • aldo-keto reductase family 1, member B1 (aldose reductase)
• Synonyms
  • AR
• Synonyms name
  • aldose reductase
• GenBank acession
  • J04795
• Locus
  7q33
• Discovery year
  1991-08-07
• Entrez gene record
  231
• Pubmed identfication
  • 1901827
• RefSeq identity
  • NM_001628
• Classification
  • Aldo-keto reductases
• VEGA ID
  OTTHUMG00000155322

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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