MET, phosphorylated (Tyr1349) (Hepatocyte Growth Factor Receptor, HGF Receptor, HGF/SF Receptor, Proto-oncogene c-Met, Scatter Factor Receptor, SF Receptor, Tyrosine-protein Kinase Met)

• Catalog number
  MBS624845
• Price
  Please ask
• Size
  5x0.05 mg

• Products_type
  Antibody
• Products_short_name
  [MET]
• Products_name_syn
  [Anti -MET, phosphorylated (Tyr1349) (Hepatocyte Growth Factor Receptor, HGF Receptor, HGF/SF Receptor, Proto-oncogene c-Met, Scatter Factor Receptor, SF Receptor, Tyrosine-protein Kinase Met)]
• Other_names
  [met proto-oncogene; met proto-oncogene; c-met/hepatocyte growth factor receptor; met proto-oncogene (hepatocyte growth factor receptor); met proto-oncogene
• Other_gene_names
  [met; c-met; met-A]
• Clonality
  Polyclonal
• Reactivity
  Human, Mouse, Rat
• Specificity
  Recognizes human Met when phosphorylated at tyrosine 1349. Species Crossreactivity: mouse, rat.
• Purity
  Affinity Purified Purified by immunoaffinity chromatography.
• Form
  Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested_application
  Western Blot (WB)
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  MET   phosphorylated   Tyr1349   Hepatocyte   Growth   Factor   Receptor   HGF   Receptor   HGF/SF   Receptor   Proto-oncogene   c-Met   Scatter   Factor   Receptor   Receptor   Tyrosine-protein   Kinase   Met  
• Gene symbol
  SOS1, HGF, IL6, SLTM, MET, TRM-CAT4-3, TRM-CAT5-1, TRM-CAT3-2, TRM-CAT7-1, TRM-CAT5-2
• Short name
  MET, phosphorylated (Tyr1349) (Hepatocyte Growth Factor Receptor, HGF Receptor, HGF/SF Receptor, Proto-oncogene c-Met, Scatter Factor Receptor, SF Receptor, Tyrosine-protein Kinase Met)
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  MET, phosphorylated (Tyr1349) (Hepatocyte Growth Factor Receptor, hepatocyte growth factor (hepapoietin A; scatter factor) Receptor, hepatocyte growth factor (hepapoietin A; scatter factor)/SF Receptor, Proto-oncogene c-Met, Scatter Factor Receptor, SF Receptor, Tyrosine-protein phosphorylation catalyst Met)
• Alternative to gene target
  hepatocyte growth factor (hepapoietin A; scatter factor), DFNB39 and F-TCF and HGFB and HPTA and SF, HGF and IDBG-24150 and ENSG00000019991 and 3082, protein heterodimerization activity, Extracellular, Hgf and IDBG-136449 and ENSMUSG00000028864 and 15234, HGF and IDBG-631194 and ENSBTAG00000017664 and 282879

Gene info

• Identity
  HGNC:11187
• Gene
  SOS1
• Long gene name
  SOS Ras/Rac guanine nucleotide exchange factor 1
• Synonyms gene
  • GINGF
• Synonyms gene name
  • gingival fibromatosis, hereditary, 1
  • son of sevenless homolog 1 (Drosophila)
• Synonyms
  • HGF
  • GF1
• GenBank acession
  • L13857
• Locus
  2p22.1
• Discovery year
  1993-10-27
• Entrez gene record
  6654
• Pubmed identfication
  • 8276400
  • 10995566
• RefSeq identity
  • NM_005633
• Classification
  • Dbl family Rho GEFs
  • Pleckstrin homology domain containing
• VEGA ID
  OTTHUMG00000102109
• Locus Specific Databases
  • LRG_754

Gene info

• Identity
  HGNC:4893
• Gene
  HGF
• Long gene name
  hepatocyte growth factor
• Synonyms gene
  • DFNB39
• Synonyms gene name
  • deafness, autosomal recessive 39
  • hepatocyte growth factor (hepapoietin A; scatter factor)
• Synonyms
  • SF
  • F-TCF
  • HGFB
  • HPTA
• Synonyms name
  • hepatopoietin A
  • fibroblast-derived tumor cytotoxic factor
  • scatter factor
  • lung fibroblast-derived mitogen
• Locus
  7q21.11
• Discovery year
  1991-06-07
• Entrez gene record
  3082
• Pubmed identfication
  • 1837206
  • 19576567
• RefSeq identity
  • NM_000601
• VEGA ID
  OTTHUMG00000023804

Gene info

• Identity
  HGNC:6018
• Gene
  IL6
• Long gene name
  interleukin 6
• Synonyms gene
  • IFNB2
• Synonyms gene name
  • interleukin 6 (interferon, beta 2)
• Synonyms
  • IL-6
  • BSF2
  • HGF
  • HSF
• Synonyms name
  • interferon, beta 2
• GenBank acession
  • M18403
• Locus
  7p15.3
• Discovery year
  1986-01-01
• Entrez gene record
  3569
• Pubmed identfication
  • 3294161
• RefSeq identity
  • NM_000600
• Classification
  • Interleukins
  • Interferons
  • Interleukin 6 type cytokine family
• VEGA ID
  OTTHUMG00000023178

Gene info

• Identity
  HGNC:20709
• Gene
  SLTM
• Long gene name
  SAFB like transcription modulator
• Synonyms
  • Met
  • FLJ13213
• GenBank acession
  • BC046119
• Locus
  15q22.1
• Discovery year
  2005-11-08
• Entrez gene record
  79811
• RefSeq identity
  • NM_024755
• Classification
  • RNA binding motif containing
• VEGA ID
  OTTHUMG00000074033

Gene info

• Identity
  HGNC:7029
• Gene
  MET
• Long gene name
  MET proto-oncogene, receptor tyrosine kinase
• Synonyms gene name
  • met proto-oncogene
• Synonyms
  • HGFR
  • RCCP2
  • DFNB97
• Synonyms name
  • hepatocyte growth factor receptor
• GenBank acession
  • M35073
• Locus
  7q31
• Discovery year
  1986-01-01
• Pubmed identfication
  • 1846706
  • 1611909
  • 25941349
• Classification
  • Receptor tyrosine kinases
  • IPT domain containing
• VEGA ID
  OTTHUMG00000023299
• Locus Specific Databases
  • LRG_662

Gene info

• Identity
  HGNC:34959
• Gene
  TRM-CAT4-3
• Long gene name
  tRNA-Met (anticodon CAT) 4-3
• Synonyms gene
  • TRNAM20
• Synonyms gene name
  • transfer RNA methionine 20 (anticodon CAU)
  • transfer RNA-Met (CAT) 4-3
• Synonyms
  • tRNA-Met-CAT-4-3
• GenBank acession
  • HG983956
• Locus
  6p22.2
• Discovery year
  2008-08-29
• Entrez gene record
  107986682
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34869
• Gene
  TRM-CAT5-1
• Long gene name
  tRNA-Met (anticodon CAT) 5-1
• Synonyms gene
  • TRNAM16
• Synonyms gene name
  • transfer RNA methionine 16 (anticodon CAU)
  • transfer RNA-Met (CAT) 5-1
• Synonyms
  • tRNA-Met-CAT-5-1
• GenBank acession
  • HG983957
• Locus
  6p22.2
• Discovery year
  2008-08-29
• Entrez gene record
  100189303
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34673
• Gene
  TRM-CAT3-2
• Long gene name
  tRNA-Met (anticodon CAT) 3-2
• Synonyms gene
  • TRNAM8
• Synonyms gene name
  • transfer RNA methionine 8 (anticodon CAU)
  • transfer RNA-Met (CAT) 3-2
• Synonyms
  • tRNA-Met-CAT-3-2
• GenBank acession
  • HG983953
• Locus
  6p22.1
• Discovery year
  2008-08-29
• Entrez gene record
  100189111
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34645
• Gene
  TRM-CAT7-1
• Long gene name
  tRNA-Met (anticodon CAT) 7-1
• Synonyms gene
  • TRNAM5
• Synonyms gene name
  • transfer RNA methionine 5 (anticodon CAU)
  • transfer RNA-Met (CAT) 7-1
• Synonyms
  • tRNA-Met-CAT-7-1
• GenBank acession
  • HG983959
• Locus
  6p11.2
• Discovery year
  2008-08-29
• Entrez gene record
  100189085
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:54713
• Gene
  TRM-CAT5-2
• Long gene name
  tRNA-Met (anticodon CAT) 5-2
• Synonyms
  • tRNA-Met-CAT-5-2
• Locus
  6p22.2
• Discovery year
  2019-12-06
• Entrez gene record
  107986680
• Classification
  • Cytoplasmic transfer RNAs

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