MART-1/Melan-A/MLANA (Melanoma Marker)
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Catalog numberMBS439964
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PricePlease ask
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Size0.02 mg (With BSA & Azide at 0.2mg/mL)
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Products_typeAntibody
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Products_short_name[MART-1/Melan-A/MLANA]
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Products_name_syn[Antigen LB39-AA; Antigen SK29-AA; Melanoma antigen recognized by T-cells 1; MLAN-A; MLANA]
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Other_names[melanoma antigen recognized by T-cells 1; Melanoma antigen recognized by T-cells 1; melanoma antigen recognized by T-cells 1; melan-A; Antigen LB39-AA; Antigen SK29-AA; Protein Melan-A]
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Products_gene_name[MLANA]
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Products_gene_name_syn[MART-1]
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Other_gene_names[MLANA; MLANA; MART1; MART-1; MART1; MART-1]
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ClonalityMonoclonal
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Clone[MLANA/1761R]
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ReactivityHuman, Mouse, Rat. Others not tested.
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SpecificityThis antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
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Form200ug/ml of Ab purified by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
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Storage_stabilityAntibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Tested_applicationFlow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin
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Gene target
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Gene symbolMLANA, RTL1, HHAT, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, SEPTIN4, TRUND-NNN7-1, IGKV1OR2-1, MIR101-1
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Short nameMART-1/Melan-A/MLANA (Melanoma )
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TechniqueComponent cell markers and DNA bp. markers are genetic markers er genes or DNA sequences with a known location on a chromosome that can be used to identify individuals or species. Protein markers in kDA.
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HostRabbit
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IsotypeIgG
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Alternative nameMART-1/Melan-A/MLANA (Melanoma detection labelled)
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Gene info
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Identity
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Gene
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Long gene namemelan-A
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Synonyms
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Locus
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Discovery year1994-08-29
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Entrez gene record
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Pubmed identfication
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameretrotransposon Gag like 1
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Synonyms gene name
- retrotransposon-like 1
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Synonyms
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Synonyms name
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Locus
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Discovery year2006-02-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Retrotransposon Gag like
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namehedgehog acyltransferase
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-09-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Membrane bound O-acyltransferases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable (II)-1-1 (pseudogene)
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Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-17
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1/206 family
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 8-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 8-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nameseptin 4
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Synonyms gene
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Synonyms gene name
- peanut-like 2 (Drosophila)
- chromosome 17 open reading frame 47
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-07-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Septins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 7-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 7-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin kappa variable 1/OR2-1 (pseudogene)
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Synonyms gene
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Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-18
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Entrez gene record
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Pubmed identfication
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Classification
- Immunoglobulin kappa (IGK) orphons
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 101-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR101 family
MeSH Data
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Name
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ConceptScope note: Experimentally induced mammary neoplasms in animals to provide a model for studying human BREAST NEOPLASMS.
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Tree numbers
- C04.588.531.500
- C04.619.590
- E05.598.500.496.843
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Qualifiersdiagnosis, parasitology, immunology, microbiology, diagnostic imaging, physiopathology, secondary, enzymology, etiology, mortality, epidemiology, blood, cerebrospinal fluid, chemically induced, congenital, diet therapy, drug therapy, therapy, chemistry, psychology, urine, virology, history, blood supply, classification, economics, embryology, genetics, nursing, radiotherapy, prevention & control, pathology, ultrastructure, metabolism, complications, surgery