MAb to Mouse CD4 (L3T4)
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Catalog numberMBS311896
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PricePlease ask
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SizeINQUIRE
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Products_typeAntibody
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Products_short_name[CD4 (L3T4)]
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Products_name_syn[Monoclonal Antibody to Mouse CD4 (L3T4), Biotin Conjugated]
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Other_names[CD4; CD4 protein; T-cell surface glycoprotein CD4; CD4 receptor; CD4 antigen (p55); OTTHUMP00000238897; T-cell surface antigen T4/Leu-3; CD4 molecule]
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Other_gene_names[CD4; CD4; CD4mut; CD4 receptor]
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ClonalityMonoclonal
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Clone[GK1.5]
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ReactivityMouse
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SpecificityRecognizes a determinant designated L3T4 present on mouse T-cell surface with an apparent molecular mass of 52 kDa. The L3T4 antigen is expressed by the helper/inducer subset of mouse T-cells. The antigen is present on approximately 80% of thymocytes, 20% of spleen cells and 60% of lymph node cells. The expression of L3T4 correlates with class II MHC antigen reactivity on cloned T-cell lines.
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PurityProtein A chromatography
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FormBiotin, Liquid
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Concentration0.5mg/ml (OD280nm)
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Storage_stabilityStore at 2 to 8°C. DO NOT FREEZE!
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Tested_applicationFlow Cytometry, Immunofluorescence Assay, Immunoprecipitation
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DescriptionCD4+ T helper cell marker or cluster differentiator of white blood cells in FACS or flow cytometry. Used offer coupled to magnetic beads. GENTAUR makes custom magnetic bead couplings on 50 and 250 nm beads for certain clones.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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Gene target
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Gene symbolCD4
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Short nameMAb Mouse CD4 (L3T4)
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TechniqueMouse, mouses
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HostRat
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IsotypeIgG2b (Rat)
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SpeciesMouse, Mouses
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Alternative namemonoclonal to Mouse CD4 molecule (L3T4)
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Alternative techniquemurine
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Alternative to gene targetCD4 molecule, CD4mut, CD4 and IDBG-15034 and ENSG00000010610 and 920, protein homodimerization activity, Cell surfaces, Cd4 and IDBG-188351 and ENSMUSG00000023274 and 12504, CD4 and IDBG-640247 and ENSBTAG00000003255 and 407098
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Gene info
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Identity
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Gene
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Long gene nameCD4 molecule
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Synonyms gene name
- CD4 antigen (p55)
- T-cell surface glycoprotein CD4
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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RefSeq identity
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Classification
- CD molecules
- C2-set domain containing
- V-set domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The number of CD4-POSITIVE T-LYMPHOCYTES per unit volume of BLOOD. Determination requires the use of a fluorescence-activated flow cytometer.
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Tree numbers
- E01.370.225.500.195.107.595.500.150
- E01.370.225.625.107.595.500.150
- E05.200.500.195.107.595.500.150
- E05.200.625.107.595.500.150
- E05.242.195.107.595.500.150
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data