MAb to Mouse CD18 (LFA-1 Beta)[CD18 (LFA-1 Beta)]

Products_type

Antibody
Reactivity

Mouse
Test

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name

Mus musculus

Gene target

MAb CD18 LFA-1 Beta [CD18 LFA-1 Beta
Gene symbol

ITGB2, ITGAL, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR101-1, MIR1289-1, MIR16-1
Short name

MAb Mouse CD18 (LFA-1 Beta)[CD18 (LFA-1 Beta)]
Technique

Mouse, mouses
Host

Host: Rat. Hybridization of S194/5.XX0.BU.1 myeloma cells with spleen cell from Lewis rat.Source: Tissue Culture
Species

Mouse, Mouses
Alternative name

monoclonal to Mouse CD18 (LFA-1 b)[CD18 (LFA-1 b)]
Alternative technique

murine

Identity

HGNC:6155
Gene

ITGB2
Long gene name

integrin subunit beta 2
Synonyms gene
- CD18
- MFI7
Synonyms gene name
- integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
- integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
Synonyms
- LFA-1
- MAC-1
Synonyms name
- complement component 3 receptor 3 and 4 subunit
GenBank acession
- AK222505
Locus

21q22.3
Discovery year

1986-01-01
Entrez gene record

3689
RefSeq identity
- NM_000211
Classification
- Integrin beta subunits
- Complement system regulators and receptors
- CD molecules
VEGA ID

OTTHUMG00000090257
Locus Specific Databases
- ITGB2base: Mutation registry for Leukocyte adhesion deficiency I (LAD-I)
- LRG_76

Identity

HGNC:6148
Gene

ITGAL
Long gene name

integrin subunit alpha L
Synonyms gene
- CD11A
Synonyms gene name
- integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
Synonyms
- LFA-1
- LFA1A
Synonyms name
- antigen CD11A (p180)
- lymphocyte function-associated antigen 1, alpha polypeptide
Locus

16p11.2
Discovery year

1986-01-01
Entrez gene record

3683
Pubmed identfication
- 3284962
Classification
- Integrin alpha subunits
- CD molecules
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000176964

Identity

HGNC:5670
Gene

IGHVII-1-1
Long gene name

immunoglobulin heavy variable (II)-1-1 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
Synonyms
- IGHV(II)-1-1
GenBank acession
- AB019441
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28377
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000152325

Identity

HGNC:5760
Gene

IGKV1OR2-1
Long gene name

immunoglobulin kappa variable 1/OR2-1 (pseudogene)
Synonyms gene
- IGKVPZ1
- IGKV1OR-1
Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
Synonyms
- IGKV1/OR-1
- IGKV1/OR2-1
GenBank acession
- Z12367
Locus

2p11.1
Discovery year

2000-04-18
Entrez gene record

3531
Pubmed identfication
- 2853098
Classification
- Immunoglobulin kappa (IGK) orphons
VEGA ID

OTTHUMG00000155081