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Products_type
Antibody
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Products_short_name
[Lipoprotein, Low Density (LDL) Receptor]
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Products_name_syn
[Monoclonal Antibody to Human/Bovine Low Density Lipoprotein (LDL) Receptor]
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Other_names
[lipoprotein]
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Clonality
Monoclonal
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Clone
[IgG-C7]
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Reactivity
Human, Bovine
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Specificity
Lipoprotein, Low Density (LDL) Receptor Recognizes an epitope in the region of repeat #1 of the ligand binding region. Addition of 15nM antibody results in inhibition of half-maximal LDL-binding.(1) Recognizes human and cow. Does not react with rat, mo
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Form
Purified, Lyophilized Reconstitute with 1ml distilled water.
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Concentration
50ug/ml (prior to lyophilization)
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Storage_stability
Store lyophilized product at 2 to 8 degree C. After reconstitution, product is stable for up to one year when stored at 2 to 8 degree C when a preservative (e.g. Thimerosal) has been added. Prepare working dilution only prior to immediate use.
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Tested_application
Flow Cytometry, Immunofluorescence Assay, Western Blot
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.