MAb to Human IgE

• Catalog number
  MBS312227
• Price
  Please ask
• Size
  5x1 mg

• Products_type
  Antibody
• Products_short_name
  [IgE]
• Products_name_syn
  [Monoclonal Antibody to Human Immunoglobulin E (IgE)]
• Clonality
  Monoclonal
• Clone
  [ME.114]
• Specificity
  IgE Recognizes human IgE. Below are the results from a standard direct immunoassay. The data indicates the degree of specificity and cross reactivity to other immunoglobulins.
• Purity
  >95% pure. Protein A chromatography
• Form
  Purified, Liquid
• Concentration
  2.8mg/ml (OD280nm, E^0.1% = 1.36)
• Storage_stability
  Upon receipt, store at -20 degree C to -80 degree C. Avoid multiple freeze/thaw cycles.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples. Immunoglobulin E (IgE) kappa or Fc specific antibody is a kind of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals. IgE is synthesized by plasma cells. Monomers of IgE consist of two heavy chains (ε chain) and two light chains, with the ε chain containing 4 Ig-like constant domains (Cε1-Cε4). IgEs play a role in allergy and response to parasite infection. High levels of IgEs caused by parasites can lower the allergic reaction of patients to allergens common present in the human environment. As such the parasite history of an allergic patient needs to be taken in consideration as a positive factor.

• Gene target
  MAb  
• Gene symbol
  MAB21L2, MAB21L1, MAB21L3
• Short name
  MAb IgE
• Technique
  IgE, IgEs
• Host
  Host: Mouse Source: Ascites
• Isotype
  IgG2b, kappa, IgE
• Species
  Human, Humans
• Alternative name
  monoclonal to H. sapiens immunoglobuline E
• Alternative technique
  immunoglobulin-e

Gene info

• Identity
  HGNC:6758
• Gene
  MAB21L2
• Long gene name
  mab-21 like 2
• Synonyms gene name
  • mab-21 (C. elegans)-like 2
  • mab-21-like 2 (C. elegans)
• GenBank acession
  • AF155219
• Locus
  4q31.3
• Discovery year
  1999-07-06
• Entrez gene record
  10586
• RefSeq identity
  • NM_006439
• Classification
  • MAB21 family
• VEGA ID
  OTTHUMG00000161442

Gene info

• Identity
  HGNC:6757
• Gene
  MAB21L1
• Long gene name
  mab-21 like 1
• Synonyms gene name
  • mab-21 (C. elegans)-like 1
  • mab-21-like 1 (C. elegans)
• Synonyms
  • CAGR1
• GenBank acession
  • BC028170
• Locus
  13q13.3
• Discovery year
  1996-08-16
• Entrez gene record
  4081
• Pubmed identfication
  • 8733127
• RefSeq identity
  • NM_005584
• Classification
  • MAB21 family
• VEGA ID
  OTTHUMG00000016723

Gene info

• Identity
  HGNC:26787
• Gene
  MAB21L3
• Long gene name
  mab-21 like 3
• Synonyms gene
  • C1orf161
• Synonyms gene name
  • chromosome 1 open reading frame 161
  • mab-21-like 3 (C. elegans)
• Synonyms
  • FLJ38716
• GenBank acession
  • AK096035
• Locus
  1p13.1
• Discovery year
  2005-07-15
• Entrez gene record
  126868
• Pubmed identfication
  • 14702039
• RefSeq identity
  • NM_152367
• Classification
  • MAB21 family
• VEGA ID
  OTTHUMG00000012110

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