MAb to Factor XII Heavy Chain

Products_type

Antibody
Products_short_name

[Factor XII (Heavy Chain)]
Products_name_syn

[Monoclonal to Factor XII Heavy Chain]
Clonality

Monoclonal
Clone

[801]
Specificity

Factor XII (Heavy Chain) Reacts with the heavy chain of human factor XII (mw~50,000) with KD of 9.8nM and partially blocks Factor XII activity. The specific epitope is located within a 20 amino acid sequence of 2.5kD in the surface binding area of Fact
Purity

Protein G chromatography
Form

Purified, Liquid
Concentration

0.66mg/ml
Storage_stability

Upon receipt, store at -20 degree C to -70 degree C. Aliquot to avoid multiple freeze/thaw cycles.
Description

Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.

Identity

HGNC:15482
Gene

SIGLEC12
Long gene name

sialic acid binding Ig like lectin 12
Synonyms gene
- SIGLECL1
Synonyms gene name
- SIGLEC-like 1
- sialic acid binding Ig-like lectin 12
- sialic acid binding Ig-like lectin 12 (gene/pseudogene)
- sialic acid binding Ig like lectin 12 (gene/pseudogene)
Synonyms
- SLG
- S2V
- Siglec-XII
- Siglec-12
- Siglec-L1
GenBank acession
- AF282256
Locus

19q13.41
Discovery year

2001-08-28
Entrez gene record

89858
Pubmed identfication
RefSeq identity
- NM_053003
Classification
- C2-set domain containing
- I-set domain containing
- Sialic acid binding Ig like lectins
- V-set domain containing
VEGA ID

OTTHUMG00000165524