Lissencephaly-1 (LIS-1, MDCR, Miller-Dieker Syndrome, MDS, PAF Acetylhydrolase 45kD Subunit, PAFAH 45kD, PAFAH alpha, PAFAH1B1, Platelet Activating Factor Acetylhydrolase Isoform Ib alpha Subunit, PAFAHA, SBH, Subcortical Band Heterotopia, ILS, Isolated L
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Catalog numberMBS608234
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PricePlease ask
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Size0.1 mg
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Products_typeAntibody
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Products_short_name[Lissencephaly-1]
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Products_name_syn[Anti -Lissencephaly-1 (LIS-1, MDCR, Miller-Dieker Syndrome, MDS, PAF Acetylhydrolase 45kD Subunit, PAFAH 45kD, PAFAH alpha, PAFAH1B1, Platelet Activating Factor Acetylhydrolase Isoform Ib alpha Subunit, PAFAHA, SBH, Subcortical Band Heterotopia, ILS, Isolated L]
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Other_names[Lissencephaly-1, isoform F; Lissencephaly-1 homolog; CG8440 gene product from transcript CG8440-RE; Lissencephaly-1, isoform E; CG8440-PE; Lis-1-PE; lissencephaly-1; Paf-AHbeta; platelet-activating factor acetylhydrolase Ib beta-subunit homolog; Lissencephaly-1, isoform D; CG8440-PD; Lis-1-PD; Lissencephaly-1, isoform A; CG8440-PA; Lis-1-PA; Lissencephaly-1, isoform C; CG8440-PC; Lis-1-PC; Lissencephaly-1, isoform B; CG8440-PB; Lis-1-PB; Lissencephaly-1, isoform F; CG8440-PF; Lis-1-PF; Lissencephaly-1]
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Other_gene_names[Lis-1; Lis-1; CG8440; D-Lis1; Dlis-1; DLis-1; DLIS-1; dLis1; Dlis1; DLis1; DLIS1; DmelCG8440; DmLIS1; l(2)k13209; l(2R)W8; Lis 1; lis-1; LIS-1; lis1; Lis1; n(2)k11702; Lis1]
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ClonalityMonoclonal
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Clone[9G377]
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ReactivityHuman
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SpecificityRecognizes human Lissencephaly-1.
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PurityAffinity Purified Purified by affinity chromatography.
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FormSupplied as a lyophilized powder in PBS, pH 7.2. Reconstitute with 100ul sterile ddH2O.
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Storage_stabilityLyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile 40-50% glycerol, ddH2O. Reconstituted product is stable for 12 months at -20 degree C. Aliquot and store at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_applicationELISA (EL/EIA), Western Blot (WB)
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DescriptionThe Lissencephaly-1 (LIS-1, MDCR, Miller-Dieker Syndrome, MDS, PAF Acetylhydrolase 45kD Subunit, PAFAH 45kD, PAFAH alpha, PAFAH1B1, Platelet Activating Factor Acetylhydrolase Isoform Ib alpha Subunit, PAFAHA, SBH, Subcortical Band Heterotopia, ILS, Isolated L is a α- or alpha protein sometimes glycoprotein present in blood. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Platelets, also called thrombocytes or cloth cells in blood and are needed to stop bleeding by clumping and clotting the blood the vessels when the an injury occurs. Teh bone marrow will produce the platelets that have no nucleus. Platelates are unique to mammals, the are curved shaped 1900nm to 3100 nm large nucleus free clothing structures.
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Gene target
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Gene symbolPAFAH1B1, PLA2G7, PEX2, PCLAF, PEX6, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1
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Short nameLissencephaly-1 (LIS-1, MDCR, Miller-Dieker Syndrome, MDS, PAF Acetylhydrolase 45kD Subunit, PAFAH 45kD, PAFAH alpha, PAFAH1B1, Platelet Activating Factor Acetylhydrolase Isoform Ib alpha Subunit, PAFAHA, SBH, Subcortical Band Heterotopia, ILS, Isolated L
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HostMouse
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IsotypeIgG
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Alternative nameLissencephaly-1 (LIS-1, MDCR, Miller-Dieker Syndrome, MDS, PAF Acetylhydrolase 45kD functionnal sequence, PAFAH 45kD, PAFAH a, platelet-activating factor acetylhydrolase 1b, regulatory functionnal sequence 1 (45kDa), Platelet Activating Factor Acetylhydrolase Isoform Ib a functionnal sequence, PAFAHA, SBH, Subcortical Band Heterotopia, ILS, Isolated L
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Alternative to gene targetplatelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa), LIS1 and LIS2 and MDCR and MDS and PAFAH, PAFAH1B1 and IDBG-16417 and ENSG00000007168 and 5048, phosphoprotein binding, nuclei, Pafah1b1 and IDBG-198862 and ENSMUSG00000020745 and 18472, PAFAH1B1 and IDBG-633101 and ENSBTAG00000016806 and 282513
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Diseasesyndrome
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Gene info
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Identity
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Gene
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Long gene nameplatelet activating factor acetylhydrolase 1b regulatory subunit 1
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Synonyms gene
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Synonyms gene name
- platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD)
- Miller-Dieker syndrome chromosome region
- platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa
- platelet-activating factor acetylhydrolase, isoform Ib, subunit 1 (45kDa)
- platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-04-03
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- WD repeat domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namephospholipase A2 group VII
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Synonyms gene name
- phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-09-20
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Entrez gene record
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Pubmed identfication
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Classification
- Phospholipases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameperoxisomal biogenesis factor 2
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Synonyms gene
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Synonyms gene name
- peroxisomal membrane protein 3 (35kD, Zellweger syndrome)
- peroxisomal membrane protein 3, 35kDa
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1992-03-03
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Peroxins
- Ring finger proteins
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namePCNA clamp associated factor
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Synonyms gene
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Synonyms gene name
- KIAA0101
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-06-24
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameperoxisomal biogenesis factor 6
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-05-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Peroxins
- AAA ATPases
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable (II)-1-1 (pseudogene)
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Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-17
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1/206 family
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 8-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 8-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 7-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 7-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin kappa variable 1/OR2-1 (pseudogene)
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Synonyms gene
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Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-18
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Entrez gene record
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Pubmed identfication
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Classification
- Immunoglobulin kappa (IGK) orphons
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VEGA ID