Lamin A, Cleavage Site (Small Subunit)
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Catalog number
MBS600805
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Price
Please ask
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Size
5x0.1 mL
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Products_type
Antibody
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Products_short_name
[Lamin A, Cleavage Site]
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Products_name_syn
[Anti -Lamin A, Cleavage Site (Small Subunit)]
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Other_names
[lamin isoform A; Prelamin-A/C; lamin; 70 kDa lamin; prelamin-A/C; lamin A/C-like 1; renal carcinoma antigen NY-REN-32; lamin A/C; 70 kDa lamin; Renal carcinoma antigen NY-REN-32]
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Other_gene_names
[LMNA; LMNA; FPL; IDC; LFP; CDDC; EMD2; FPLD; HGPS; LDP1; LMN1; LMNC; PRO1; CDCD1; CMD1A; FPLD2; LMNL1; CMT2B1; LGMD1B; LMN1]
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Clonality
Monoclonal
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Clone
[3A5]
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Reactivity
Human, Mouse, Rat
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Specificity
Detects endogenous levels of the small fragment of lamin A when cleaved by caspase-6 at Asp230. It is a marker of caspase-6 activity. Detects the small fragment of lamin A/C only when cleaved at Asp230. Does not crossreact with full length lamin A (nor with lamin C). Species Crossreactivity: Mouse and rat.
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Purity
Purified Purified.
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Form
Supplied as a liquid in 10mM HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol, 0.02% sodium azide.
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Storage_stability
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_application
ELISA (EL/EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
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Gene target
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Short name
Lamin A, Cleavage Site ( Subunit)
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Host
Mouse
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Isotype
IgG1
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Alternative name
Lamin A, Cleavage Site (Small functionnal sequence)
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