LAG-3 (Lymphocyte Activation Gene-3, FDC Protein, CD223)

• Catalog number
  MBS608941
• Price
  Please ask
• Size
  5x0.25 mg

• Products_type
  Antibody
• Products_short_name
  [LAG-3]
• Products_name_syn
  [Anti -LAG-3 (Lymphocyte Activation Gene-3, FDC Protein, CD223)]
• Other_names
  [LAG-3 protein]
• Clonality
  Monoclonal
• Clone
  [7E155]
• Reactivity
  Mouse
• Specificity
  Recognizes murine lymphocyte activation gene-3 (LAG-3). Recognizes an epitope within the D2 domain of CD223. Reported to block the in vitro function of murine LAG-3 but studies suggest that the antibody does not block binding of LAG-3 to MHC class II.
• Purity
  Affinity Purified Purified by Protein G affinity chromatography.
• Form
  Supplied as a liquid in PBS, pH 7.4 0.09% sodium azide.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested_application
  Flow Cytometry (FC/FACS)
• Description
  cDNA genes are a locus (or region) of DNA for functional transcript RNA or protein. An ELISA is used to detect the expressed protein in biological fluids, serum, saliva.

• Gene target
  LAG-3   Lymphocyte   Activation   Gene-3   FDC   Protein   CD223  
• Gene symbol
  LAG3, FDCSP, GNLY, MIR1302-3, MIR509-3, MIR7-3, PIRC14, PIRC12
• Short name
  LAG-3 (Lymphocyte Activation -3, FDC Protein, CD223)
• Technique
  activation
• Host
  Rat
• Isotype
  IgG1
• Alternative name
  LAG-3 (Lymphocyte Activation Gene-3, FDC Protein, CD223)
• Tissue
  lymphocyte

Gene info

• Identity
  HGNC:6476
• Gene
  LAG3
• Long gene name
  lymphocyte activating 3
• Synonyms gene name
  • lymphocyte-activation gene 3
• Synonyms
  • CD223
• Locus
  12p13.31
• Discovery year
  1991-06-03
• Entrez gene record
  3902
• RefSeq identity
  • NM_002286
• Classification
  • Immunoglobulin like domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000169197

Gene info

• Identity
  HGNC:19215
• Gene
  FDCSP
• Long gene name
  follicular dendritic cell secreted protein
• Synonyms gene
  • C4orf7
• Synonyms gene name
  • chromosome 4 open reading frame 7
• Synonyms
  • FDC-SP
• GenBank acession
  • AF435080
• Locus
  4q13.3
• Discovery year
  2002-09-17
• Entrez gene record
  260436
• Pubmed identfication
  • 12193705
  • 17548624
  • 20811673
• RefSeq identity
  • NM_152997
• VEGA ID
  OTTHUMG00000129393

Gene info

• Identity
  HGNC:4414
• Gene
  GNLY
• Long gene name
  granulysin
• Synonyms gene
  • LAG2
• Synonyms
  • NKG5
  • LAG-2
  • D2S69E
  • TLA519
• Synonyms name
  • T-lymphocyte activation gene 519
• GenBank acession
  • X54101
• Locus
  2p11.2
• Discovery year
  1999-11-22
• Entrez gene record
  10578
• Pubmed identfication
  • 2212946
  • 2434598
• RefSeq identity
  • NM_006433
• VEGA ID
  OTTHUMG00000130179

Gene info

• Identity
  HGNC:35295
• Gene
  MIR1302-3
• Long gene name
  microRNA 1302-3
• Synonyms gene
  • MIRN1302-3
• Synonyms
  • hsa-mir-1302-3
• Locus
  2q14.1
• Discovery year
  2008-11-03
• Entrez gene record
  100302128
• RefSeq identity
  • NR_031632
• Classification
  • MicroRNA MIR1302 family

Gene info

• Identity
  HGNC:33675
• Gene
  MIR509-3
• Long gene name
  microRNA 509-3
• Synonyms gene
  • MIRN509-3
• Synonyms
  • hsa-mir-509-3
• Locus
  Xq27.3
• Discovery year
  2007-10-24
• Entrez gene record
  100126337
• RefSeq identity
  • NR_030629
• Classification
  • MicroRNA MIR506 family

Gene info

• Identity
  HGNC:31640
• Gene
  MIR7-3
• Long gene name
  microRNA 7-3
• Synonyms gene
  • MIRN7-3
• Synonyms
  • hsa-mir-7-3
• Locus
  19p13.3
• Discovery year
  2004-04-23
• Entrez gene record
  407045
• RefSeq identity
  • NR_029607
• Classification
  • MicroRNA MIR7 family

Gene info

• Identity
  HGNC:37518
• Gene
  PIRC14
• Long gene name
  piwi-interacting RNA cluster 14
• Locus
  3
• Discovery year
  2009-11-05
• Entrez gene record
  100313784
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37516
• Gene
  PIRC12
• Long gene name
  piwi-interacting RNA cluster 12
• Locus
  3
• Discovery year
  2009-11-05
• Entrez gene record
  100313808
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

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