KLRK1 (Killer Cell Lectin-like Receptor Subfamily K Member 1, CD314, HGNC:18788, D12S2489E, NK Cell Receptor D, NK Lectin-like Receptor, NKLLR, NKG2D Activating NK Receptor, NKG2D Type II Integral Membrane Protein, NKR P2) (PE)
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Catalog number
MBS604694
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Price
Please ask
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Size
5x100 Tests
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Products_type
Antibody
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Products_short_name
[KLRK1]
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Products_name_syn
[Anti -KLRK1 (Killer Cell Lectin-like Receptor Subfamily K Member 1, CD314, HGNC:18788, D12S2489E, NK Cell Receptor D, NK Lectin-like Receptor, NKLLR, NKG2D Activating NK Receptor, NKG2D Type II Integral Membrane Protein, NKR P2) (PE)]
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Other_names
[Klrk1; Klrk1 protein; NKG2-D type II integral membrane protein; NK cell receptor D; natural killer cell group 2D; NKG2-D-activating NK receptor; killer cell lectin-like receptor subfamily K, member 1; NKG2-D-activating NK receptor; NK cell receptor D; Killer cell lectin-like receptor subfamily K member 1]
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Other_gene_names
[Klrk1; Klrk1; Nkg2d; NKG2-D; D6H12S2489E; Nkg2d]
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Clonality
Monoclonal
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Clone
[10B1393]
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Reactivity
Human
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Specificity
Recognizes human KLRK1. Inhibits T cell recognition of MICA a ligand of KLRK1.
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Purity
Affinity Purified Purified by Protein G affinity chromatography.
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Form
Supplied as a lyophilized powder from PBS, pH 7.4, 1% BSA, 0.09% sodium azide. Labeled with R-Phycoerythrin (PE). Reconstitute with 1ml sterile 40-50% glycerol, ddH2O.
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Storage_stability
May be stored at 4 degree C before opening. DO NOT FREEZE! Stable at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months at 4 degree C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.
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Tested_application
Flow Cytometry (FC/FACS)
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Description
For cells, cell lines and tissues in culture till half confluency. Associated membrane protein types are lipopolysaccharide selective barriers. Biological membranes include cell membranes, outer coverings of cells or organelles that allow passage of certain proteins and nuclear membranes, which cover a cell nucleus; and tissue membranes, such as mucosae and serosae. , The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
KLRK1, KLRB1, KLRC4-KLRK1, KLRK1-AS1, TACR3
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Short name
KLRK1 (Killer Lectin-like Receptor Subfamily K Member 1, CD314, HGNC:18788, D12S2489E, NK Receptor D, NK Lectin-like Receptor, NKLLR, NKG2D Activating NK Receptor, NKG2D II Integral Protein, NKR P2) (PE)
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Host
Mouse
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Isotype
IgG1
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Label
PE
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Alternative name
NKG2-D classification II integral membrane protein (Killer cellular Lectin-like Receptor Subfamily K Member 1, CD314, HGNC:18788, D12S2489E, NK cellular Receptor D, NK Lectin-like Receptor, NKLLR, NKG2D Activating NK Receptor, NKG2D classification II Integral Membrane Protein, NKR P2) (peroxidase)
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Alternative to gene target
NKG2-D type II integral membrane protein, CD314 and D12S2489E and KLR and NKG2-D and NKG2D, KLRK1 and IDBG-546188 and ENSG00000255819 and 100528032,22914, multiple
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Tissue
cell
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Gene info
Gene info
Gene info
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Identity
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Gene
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Long gene name
KLRC4-KLRK1 readthrough
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Locus
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Discovery year
2013-09-25
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Entrez gene record
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
KLRK1 antisense RNA 1
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Synonyms
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Locus
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Discovery year
2020-04-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
Gene info
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Identity
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Gene
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Long gene name
tachykinin receptor 3
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1997-11-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Electrophoresis in which a second perpendicular electrophoretic transport is performed on the separate components resulting from the first electrophoresis. This technique is usually performed on polyacrylamide gels.
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Tree numbers
- E05.196.401.250
- E05.301.300.230
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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