KLRK1 (Killer Cell Lectin-like Receptor Subfamily K Member 1, CD314, HGNC:18788, D12S2489E, NK Cell Receptor D, NK Lectin-like Receptor, NKLLR, NKG2D Activating NK Receptor, NKG2D Type II Integral Membrane Protein, NKR P2) (FITC)

• Catalog number
  MBS608130
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Antibody
• Products_short_name
  [KLRK1]
• Products_name_syn
  [Anti -KLRK1 (Killer Cell Lectin-like Receptor Subfamily K Member 1, CD314, HGNC:18788, D12S2489E, NK Cell Receptor D, NK Lectin-like Receptor, NKLLR, NKG2D Activating NK Receptor, NKG2D Type II Integral Membrane Protein, NKR P2) (FITC)]
• Other_names
  [Klrk1; Klrk1 protein; NKG2-D type II integral membrane protein; NK cell receptor D; natural killer cell group 2D; NKG2-D-activating NK receptor; killer cell lectin-like receptor subfamily K, member 1; NKG2-D-activating NK receptor; NK cell receptor D; Killer cell lectin-like receptor subfamily K member 1]
• Other_gene_names
  [Klrk1; Klrk1; Nkg2d; NKG2-D; D6H12S2489E; Nkg2d]
• Clonality
  Monoclonal
• Clone
  [10B1392]
• Reactivity
  Human
• Specificity
  Recognizes human KLRK1. Inhibits T cell recognition of MICA a ligand of KLRK1.
• Purity
  Affinity Purified Purified by Protein G affinity chromatography.
• Form
  Supplied as a liquid in PBS, pH 7.4, 1% BSA, 0.09% sodium azide. Labeled with fluorescein isothiocyanate (FITC).
• Storage_stability
  May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. FITC conjugates are sensitive to light.
• Tested_application
  Flow Cytometry (FC/FACS)
• Description
  For cells, cell lines and tissues in culture till half confluency. Associated membrane protein types are lipopolysaccharide selective barriers. Biological membranes include cell membranes, outer coverings of cells or organelles that allow passage of certain proteins and nuclear membranes, which cover a cell nucleus; and tissue membranes, such as mucosae and serosae. , The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Properties
  This MyBioSource Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. MyBioSource FITC is highly sensitive to pH extremes.
• Conjugation
  Anti-FITC Antibody

• Gene target
  KLRK1   Killer   Lectin-like   Receptor   Subfamily   Member   CD314   HGNC   18788   D12S2489E   Receptor   Lectin-like   Receptor   NKLLR   NKG2D   Activating   Receptor   NKG2D   Integral   Membrane   Protein   NKR  
• Gene symbol
  KLRK1, KLRB1, KLRC4-KLRK1, KLRK1-AS1, TACR3
• Short name
  KLRK1 (Killer Lectin-like Receptor Subfamily K Member 1, CD314, HGNC:18788, D12S2489E, NK Receptor D, NK Lectin-like Receptor, NKLLR, NKG2D Activating NK Receptor, NKG2D II Integral Protein, NKR P2) (FITC)
• Technique
  FITC, Fluorescein
• Host
  Mouse
• Isotype
  IgG1
• Label
  FITC
• Alternative name
  NKG2-D classification II integral membrane protein (Killer cellular Lectin-like Receptor Subfamily K Member 1, CD314, HGNC:18788, D12S2489E, NK cellular Receptor D, NK Lectin-like Receptor, NKLLR, NKG2D Activating NK Receptor, NKG2D classification II Integral Membrane Protein, NKR P2) (fluorecein)
• Alternative technique
  fluorescine
• Alternative to gene target
  NKG2-D type II integral membrane protein, CD314 and D12S2489E and KLR and NKG2-D and NKG2D, KLRK1 and IDBG-546188 and ENSG00000255819 and 100528032,22914, multiple
• Tissue
  cell

Gene info

• Identity
  HGNC:18788
• Gene
  KLRK1
• Long gene name
  killer cell lectin like receptor K1
• Synonyms gene
  • D12S2489E
• Synonyms gene name
  • DNA segment on chromosome 12 (unique) 2489 expressed sequence
  • killer cell lectin-like receptor subfamily K, member 1
• Synonyms
  • NKG2D
  • KLR
  • NKG2-D
  • CD314
• GenBank acession
  • AJ001687
• Locus
  12p13.2
• Discovery year
  2003-12-12
• Entrez gene record
  22914
• Pubmed identfication
  • 9683661
  • 2007850
• RefSeq identity
  • NM_007360
• Classification
  • Killer cell lectin like receptors
  • C-type lectin domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000168574

Gene info

• Identity
  HGNC:6373
• Gene
  KLRB1
• Long gene name
  killer cell lectin like receptor B1
• Synonyms gene
  • NKR
• Synonyms gene name
  • killer cell lectin-like receptor subfamily B, member 1
• Synonyms
  • CD161
  • NKR-P1
  • NKR-P1A
  • hNKR-P1A
  • CLEC5B
• Synonyms name
  • natural killer cell surface protein P1A
• GenBank acession
  • U11276
• Locus
  12p13.31
• Discovery year
  1998-01-16
• Entrez gene record
  3820
• Pubmed identfication
  • 8077657
• RefSeq identity
  • NM_002258
• Classification
  • Killer cell lectin like receptors
  • C-type lectin domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000168581

Gene info

• Identity
  HGNC:48357
• Gene
  KLRC4-KLRK1
• Long gene name
  KLRC4-KLRK1 readthrough
• Locus
  12p13.2
• Discovery year
  2013-09-25
• Entrez gene record
  100528032
• VEGA ID
  OTTHUMG00000168531

Gene info

• Identity
  HGNC:54868
• Gene
  KLRK1-AS1
• Long gene name
  KLRK1 antisense RNA 1
• Synonyms
  • LOC101928100
• Locus
  12p13.2
• Discovery year
  2020-04-01
• Entrez gene record
  101928100
• Pubmed identfication
  • 32216054
• RefSeq identity
  • NR_120430
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:11528
• Gene
  TACR3
• Long gene name
  tachykinin receptor 3
• Synonyms
  • NK3R
  • NKR
  • TAC3R
• Synonyms name
  • neurokinin beta receptor
  • neuromedin-K receptor
  • neurokinin B receptor
  • NK3 receptor
• GenBank acession
  • M89473
• Locus
  4q24
• Discovery year
  1997-11-28
• Entrez gene record
  6870
• Pubmed identfication
  • 1374246
  • 19079066
• RefSeq identity
  • NM_001059
• Classification
  • Tachykinin receptors
• VEGA ID
  OTTHUMG00000131124

MeSH Data

• Name
  Electrophoresis, Gel, Two-Dimensional
• Concept
  Scope note: Electrophoresis in which a second perpendicular electrophoretic transport is performed on the separate components resulting from the first electrophoresis. This technique is usually performed on polyacrylamide gels.
• Tree numbers
  • E05.196.401.250
  • E05.301.300.230
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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