KIR2DL3, Recombinant, Human (p58 KIR, CD158, cl-6, KIR-K7, NKAT2, NKR-K7, Killer Cell Immunoglobulin (Ig)-like Receptor)

• Catalog number
  MBS637742
• Price
  Please ask
• Size
  0.005 mg

• Products_type
  Recombinant Protein
• Products_short_name
  [KIR2DL3]
• Other_names
  [KIR2DL3; Killer cell immunoglobulin-like receptor 2DL3; killer cell immunoglobulin-like receptor 2DL3; NKAT-2; NK-receptor; p58 NK receptor CL-6; MHC class I NK cell receptor; killer inhibitory receptor cl 2-3; CD158 antigen-like family member B2; natural killer associated transcript 2; natural killer-associated transcript 2; p58.2 MHC class-I specific NK receptor; p58.2 MHC class-I-specific NK receptor; p58 natural killer cell receptor clone CL-6; natural killer cell inhibitory receptor KIR2DL3; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3; CD158 antigen-like family member B2; KIR-023GB; Killer inhibitory receptor cl 2-3; MHC class I NK cell receptor; NKAT2a; NKAT2b; Natural killer-associated transcript 2; NKAT-2; p58 natural killer cell receptor clone CL-6; p58 NK receptor CL-6; p58.2 MHC class-I-specific NK receptor]
• Other_gene_names
  [KIR2DL3; KIR2DL3; p58; NKAT; GL183; NKAT2; CD158b; NKAT2A; NKAT2B; CD158B2; KIR-K7b; KIR-K7c; KIRCL23; KIR-023GB; CD158B2; KIRCL23; NKAT2; NKAT-2]
• Purity
  Highly Purified95% as determined by RP-HPLC, anion-exchange FPLC and/or reducing and non-reducing SDS-PAGE Silver Stained gel.
• Form
  Supplied as a liquid in 25mM Tris-HCl, pH 7.5.
• Storage_stability
  -20 degree CStability: Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
• Description
  For cells, cell lines and tissues in culture till half confluency. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  KIR2DL3   p58   KIR   CD158   cl-6   KIR-K7   NKAT2   NKR-K7   Killer   Immunoglobulin   like   Receptor  
• Gene symbol
  GEM, RBPJP4, KRT7, KIR2DL3, KLRB1, KIR3DL1, TACR3
• Short name
  KIR2DL3, Recombinant, (p58 KIR, CD158, cl-6, KIR-K7, NKAT2, NKR-K7, Killer Immunoglobulin (Ig)-like Receptor)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  E Coli
• Species
  Human, Humans
• Alternative name
  killer cellular immunoglobulin-like receptor, two domains, large cytoplasmic tail, 3, Rec., H. sapiens (p58 KIR, CD158, cl-6, KIR-K7, NKAT2, NKR-K7, Killer cellular Immunoglobulin (Ig)-like Receptor)
• Alternative technique
  rec
• Alternative to gene target
  killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3, CD158b and CD158B2 and GL183 and KIR-023GB and KIR-K7b and KIR-K7c and KIR2DS5 and KIRCL23 and NKAT and NKAT2 and NKAT2A and NKAT2B and p58, KIR2DL3 and IDBG-409456 and ENSG00000243772 and 3804, protein binding, Plasma membranes
• Tissue
  cell

Gene info

• Identity
  HGNC:4234
• Gene
  GEM
• Long gene name
  GTP binding protein overexpressed in skeletal muscle
• Synonyms gene name
  • GTP-binding protein overexpressed in skeletal muscle
• Synonyms
  • KIR
• Synonyms name
  • kinase-inducible Ras-like protein
• Locus
  8q22.1
• Discovery year
  1995-08-15
• Entrez gene record
  2669
• Pubmed identfication
  • 7912851
  • 11956230
• RefSeq identity
  • NM_181702
• Classification
  • RGK type GTPase family
• VEGA ID
  OTTHUMG00000164392

Gene info

• Identity
  HGNC:13687
• Gene
  RBPJP4
• Long gene name
  RBPJ pseudogene 4
• Synonyms gene
  • RBPSUHP4
• Synonyms gene name
  • recombining binding protein suppressor of hairless (Drosophila) pseudogene 4
  • rec
• Synonyms
  • K7
• GenBank acession
  • L34544
• Locus
  9q13
• Discovery year
  2000-09-28
• Entrez gene record
  58163
• Pubmed identfication
  • 7873751

Gene info

• Identity
  HGNC:6445
• Gene
  KRT7
• Long gene name
  keratin 7
• Synonyms gene name
  • keratin 7, type II
• Synonyms
  • K7
  • CK7
  • K2C7
  • SCL
• Synonyms name
  • keratin, type II cytoskeletal 7
  • cytokeratin 7
  • sarcolectin
  • keratin, 55K type II cytoskeletal
• Locus
  12q13.13
• Discovery year
  1991-09-12
• Entrez gene record
  3855
• Pubmed identfication
  • 1713141
  • 16831889
• RefSeq identity
  • NM_005556
• Classification
  • Keratins, type II
• VEGA ID
  OTTHUMG00000169580

Gene info

• Identity
  HGNC:6331
• Gene
  KIR2DL3
• Long gene name
  killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3
• Synonyms gene name
  • killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
• Synonyms
  • cl-6
  • nkat2
  • nkat2a
  • nkat2b
  • p58
  • CD158B2
• GenBank acession
  • L41268
• Locus
  19q13.42
• Discovery year
  1997-11-14
• Entrez gene record
  3804
• Pubmed identfication
  • 7749980
  • 8662091
• Classification
  • Killer cell immunoglobulin like receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000065887
• Locus Specific Databases
  • IPD-KIR Database

Gene info

• Identity
  HGNC:6373
• Gene
  KLRB1
• Long gene name
  killer cell lectin like receptor B1
• Synonyms gene
  • NKR
• Synonyms gene name
  • killer cell lectin-like receptor subfamily B, member 1
• Synonyms
  • CD161
  • NKR-P1
  • NKR-P1A
  • hNKR-P1A
  • CLEC5B
• Synonyms name
  • natural killer cell surface protein P1A
• GenBank acession
  • U11276
• Locus
  12p13.31
• Discovery year
  1998-01-16
• Entrez gene record
  3820
• Pubmed identfication
  • 8077657
• RefSeq identity
  • NM_002258
• Classification
  • Killer cell lectin like receptors
  • C-type lectin domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000168581

Gene info

• Identity
  HGNC:6338
• Gene
  KIR3DL1
• Long gene name
  killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
• Synonyms gene
  • KIR
• Synonyms gene name
  • killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
• Synonyms
  • cl-2
  • NKB1
  • cl-11
  • nkat3
  • NKB1B
  • AMB11
  • CD158e1/2
  • CD158E1
  • CD158e2
• GenBank acession
  • L41269
• Locus
  19q13.42
• Discovery year
  1995-12-20
• Entrez gene record
  3811
• Pubmed identfication
  • 7716543
  • 7749980
• RefSeq identity
  • NM_013289
• Classification
  • Killer cell immunoglobulin like receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000065933
• Locus Specific Databases
  • IPD-KIR Database

Gene info

• Identity
  HGNC:11528
• Gene
  TACR3
• Long gene name
  tachykinin receptor 3
• Synonyms
  • NK3R
  • NKR
  • TAC3R
• Synonyms name
  • neurokinin beta receptor
  • neuromedin-K receptor
  • neurokinin B receptor
  • NK3 receptor
• GenBank acession
  • M89473
• Locus
  4q24
• Discovery year
  1997-11-28
• Entrez gene record
  6870
• Pubmed identfication
  • 1374246
  • 19079066
• RefSeq identity
  • NM_001059
• Classification
  • Tachykinin receptors
• VEGA ID
  OTTHUMG00000131124

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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