KIR2DL3 (p58 KIR, CD158, cl-6, KIR-K7, NKAT2, NKR-K7, Killer Cell Immunoglobulin (Ig)-like Receptor)

• Catalog number
  MBS633243
• Price
  Please ask
• Size
  0.1 mL

• Products_type
  Antibody
• Products_short_name
  [KIR2DL3]
• Products_name_syn
  [Anti -KIR2DL3 (p58 KIR, CD158, cl-6, KIR-K7, NKAT2, NKR-K7, Killer Cell Immunoglobulin (Ig)-like Receptor)]
• Other_names
  [killer cell immunoglobulin-like receptor 2DL3; Killer cell immunoglobulin-like receptor 2DL3; killer cell immunoglobulin-like receptor 2DL3; NKAT-2; NK-receptor; OTTHUMP00000068619; p58 NK receptor CL-6; MHC class I NK cell receptor; killer inhibitory receptor cl 2-3; CD158 antigen-like family member B2; natural killer associated transcript 2; natural killer-associated transcript 2; p58.2 MHC class-I specific NK receptor; p58.2 MHC class-I-specific NK receptor; p58 natural killer cell receptor clone CL-6; natural killer cell inhibitory receptor KIR2DL3; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3; CD158 antigen-like family member B2; KIR-023GB; Killer inhibitory receptor cl 2-3; MHC class I NK cell receptor; NKAT2a; NKAT2b; Natural killer-associated transcript 2; NKAT-2; p58 natural killer cell receptor clone CL-6; p58 NK receptor CL-6; p58.2 MHC class-I-specific NK receptor]
• Other_gene_names
  [KIR2DL3; KIR2DL3; p58; NKAT; GL183; NKAT2; CD158b; NKAT2A; NKAT2B; CD158B2; KIR-K7b; KIR-K7c; KIRCL23; KIR-023GB; MGC129943; CD158B2; KIRCL23; NKAT2]
• Clonality
  Monoclonal
• Clone
  [4k10]
• Reactivity
  Human
• Specificity
  Recognizes the extracellular domain of the KIR2DL3.
• Purity
  Affinity Purified Purified from mouse ascitic fluid by Protein G affinity chromatography. 95% (SDS-PAGE).
• Form
  Supplied as a liquid in PBS, pH 7.4., 40% glycerol.
• Storage_stability
  May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS)
• Description
  For cells, cell lines and tissues in culture till half confluency. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  KIR2DL3   p58   KIR   CD158   cl-6   KIR-K7   NKAT2   NKR-K7   Killer   Immunoglobulin   like   Receptor  
• Gene symbol
  GEM, RBPJP4, KRT7, KIR2DL3, KLRB1, KIR3DL1, TACR3
• Short name
  KIR2DL3 (p58 KIR, CD158, cl-6, KIR-K7, NKAT2, NKR-K7, Killer Immunoglobulin (Ig)-like Receptor)
• Host
  Mouse
• Isotype
  IgG2a,k
• Alternative name
  killer cellular immunoglobulin-like receptor, two domains, large cytoplasmic tail, 3 (p58 KIR, CD158, cl-6, KIR-K7, NKAT2, NKR-K7, Killer cellular Immunoglobulin (Ig)-like Receptor)
• Alternative to gene target
  killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3, CD158b and CD158B2 and GL183 and KIR-023GB and KIR-K7b and KIR-K7c and KIR2DS5 and KIRCL23 and NKAT and NKAT2 and NKAT2A and NKAT2B and p58, KIR2DL3 and IDBG-409456 and ENSG00000243772 and 3804, protein binding, Plasma membranes
• Tissue
  cell

Gene info

• Identity
  HGNC:4234
• Gene
  GEM
• Long gene name
  GTP binding protein overexpressed in skeletal muscle
• Synonyms gene name
  • GTP-binding protein overexpressed in skeletal muscle
• Synonyms
  • KIR
• Synonyms name
  • kinase-inducible Ras-like protein
• Locus
  8q22.1
• Discovery year
  1995-08-15
• Entrez gene record
  2669
• Pubmed identfication
  • 7912851
  • 11956230
• RefSeq identity
  • NM_181702
• Classification
  • RGK type GTPase family
• VEGA ID
  OTTHUMG00000164392

Gene info

• Identity
  HGNC:13687
• Gene
  RBPJP4
• Long gene name
  RBPJ pseudogene 4
• Synonyms gene
  • RBPSUHP4
• Synonyms gene name
  • recombining binding protein suppressor of hairless (Drosophila) pseudogene 4
  • rec
• Synonyms
  • K7
• GenBank acession
  • L34544
• Locus
  9q13
• Discovery year
  2000-09-28
• Entrez gene record
  58163
• Pubmed identfication
  • 7873751

Gene info

• Identity
  HGNC:6445
• Gene
  KRT7
• Long gene name
  keratin 7
• Synonyms gene name
  • keratin 7, type II
• Synonyms
  • K7
  • CK7
  • K2C7
  • SCL
• Synonyms name
  • keratin, type II cytoskeletal 7
  • cytokeratin 7
  • sarcolectin
  • keratin, 55K type II cytoskeletal
• Locus
  12q13.13
• Discovery year
  1991-09-12
• Entrez gene record
  3855
• Pubmed identfication
  • 1713141
  • 16831889
• RefSeq identity
  • NM_005556
• Classification
  • Keratins, type II
• VEGA ID
  OTTHUMG00000169580

Gene info

• Identity
  HGNC:6331
• Gene
  KIR2DL3
• Long gene name
  killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3
• Synonyms gene name
  • killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
• Synonyms
  • cl-6
  • nkat2
  • nkat2a
  • nkat2b
  • p58
  • CD158B2
• GenBank acession
  • L41268
• Locus
  19q13.42
• Discovery year
  1997-11-14
• Entrez gene record
  3804
• Pubmed identfication
  • 7749980
  • 8662091
• Classification
  • Killer cell immunoglobulin like receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000065887
• Locus Specific Databases
  • IPD-KIR Database

Gene info

• Identity
  HGNC:6373
• Gene
  KLRB1
• Long gene name
  killer cell lectin like receptor B1
• Synonyms gene
  • NKR
• Synonyms gene name
  • killer cell lectin-like receptor subfamily B, member 1
• Synonyms
  • CD161
  • NKR-P1
  • NKR-P1A
  • hNKR-P1A
  • CLEC5B
• Synonyms name
  • natural killer cell surface protein P1A
• GenBank acession
  • U11276
• Locus
  12p13.31
• Discovery year
  1998-01-16
• Entrez gene record
  3820
• Pubmed identfication
  • 8077657
• RefSeq identity
  • NM_002258
• Classification
  • Killer cell lectin like receptors
  • C-type lectin domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000168581

Gene info

• Identity
  HGNC:6338
• Gene
  KIR3DL1
• Long gene name
  killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
• Synonyms gene
  • KIR
• Synonyms gene name
  • killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
• Synonyms
  • cl-2
  • NKB1
  • cl-11
  • nkat3
  • NKB1B
  • AMB11
  • CD158e1/2
  • CD158E1
  • CD158e2
• GenBank acession
  • L41269
• Locus
  19q13.42
• Discovery year
  1995-12-20
• Entrez gene record
  3811
• Pubmed identfication
  • 7716543
  • 7749980
• RefSeq identity
  • NM_013289
• Classification
  • Killer cell immunoglobulin like receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000065933
• Locus Specific Databases
  • IPD-KIR Database

Gene info

• Identity
  HGNC:11528
• Gene
  TACR3
• Long gene name
  tachykinin receptor 3
• Synonyms
  • NK3R
  • NKR
  • TAC3R
• Synonyms name
  • neurokinin beta receptor
  • neuromedin-K receptor
  • neurokinin B receptor
  • NK3 receptor
• GenBank acession
  • M89473
• Locus
  4q24
• Discovery year
  1997-11-28
• Entrez gene record
  6870
• Pubmed identfication
  • 1374246
  • 19079066
• RefSeq identity
  • NM_001059
• Classification
  • Tachykinin receptors
• VEGA ID
  OTTHUMG00000131124

MeSH Data

• Name
  Electrophoresis, Gel, Two-Dimensional
• Concept
  Scope note: Electrophoresis in which a second perpendicular electrophoretic transport is performed on the separate components resulting from the first electrophoresis. This technique is usually performed on polyacrylamide gels.
• Tree numbers
  • E05.196.401.250
  • E05.301.300.230
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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