Kininogen, High MW (High Molecular Weight Kininogen, HMWK, KNG, Kininogen 1, Kininogen-1, KNG1, Alpha-2-thiol Proteinase Inhibitor, BDK, Fitzgerald Factor, Williams-Fitzgerald-Flaujeac Factor)

• Catalog number
  MBS644136
• Price
  Please ask
• Size
  5x1 mL

• Products_type
  Antibody
• Products_short_name
  [Kininogen, High MW]
• Products_name_syn
  [Anti -Kininogen, High MW (High Molecular Weight Kininogen, HMWK, KNG, Kininogen 1, Kininogen-1, KNG1, Alpha-2-thiol Proteinase Inhibitor, BDK, Fitzgerald Factor, Williams-Fitzgerald-Flaujeac Factor)]
• Other_names
  [kininogen II,high MW]
• Clonality
  Polyclonal
• Reactivity
  Human
• Specificity
  Recognizes human high molecular weight kininogen. In immunoelectrophoresis, bi-dimensional electrophoresis and radial immunodiffusion (Ouchterlony, Mancini) against normal plasma, one single precipitin line is obtained. No precipitation is observed against plasma of patients with high molecular weight kininogen deficiency, but its presence can be demonstrated in normal serum. In double radial immunodiffusion the precipitin line obtained against normal plasma shows a reaction of full identity with the precipitin line with purified high molecular weight kininogen. Does not crossreact with any other human plasma proteins.
• Purity
  Serum Serum
• Form
  Supplied as a lyophilized powder. Preservative free. Reconstitute with 1ml sterile ddH2O. Dilute further in PBS, pH 7.2.
• Storage_stability
  Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  ELISA (EL/EIA)
• Description
  The Kininogen, MW ( Molecular Weight Kininogen, HMWK, KNG, Kininogen 1, Kininogen-1, KNG1, Alpha-2-thiol Proteinase Inhibitor, BDK, Fitzgerald Factor, Williams-Fitzgerald-Flaujeac Factor) is a α- or alpha protein sometimes glycoprotein present in blood. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

• Gene target
  Kininogen   Molecular   Weight   Kininogen   HMWK   KNG   Kininogen   Kininogen-1   KNG1   Alpha-2-thiol   Proteinase   Inhibitor   BDK   Fitzgerald   Factor   Williams-Fitzgerald-Flaujeac   Factor  
• Gene symbol
  KNG1, MIR7-2, MIR329-2, MIR512-2, MIR521-2, MIR1289-2, MIR509-2, KRTAP13-2, RNU6-2, SNORD116-2
• Short name
  Kininogen, MW ( Molecular Weight Kininogen, HMWK, KNG, Kininogen 1, Kininogen-1, KNG1, Alpha-2-thiol Proteinase Inhibitor, BDK, Fitzgerald Factor, Williams-Fitzgerald-Flaujeac Factor)
• Host
  Goat
• Isotype
  IgG
• Alternative name
  Kininogen, High MW (High Molecular Weight Kininogen, HMWK, KNG, Kininogen 1, Kininogen-1, kininogen 1, a-2-thiol Proteinase suppressor, BDK, Fitzgerald Factor, Williams-Fitzgerald-Flaujeac Factor)
• Alternative to gene target
  kininogen 1, BDK and BK and KNG, KNG1 and IDBG-69059 and ENSG00000113889 and 3827, zinc ion binding, Extracellular, KNG1 and IDBG-634652 and ENSBTAG00000005122 and 280833

Gene info

• Identity
  HGNC:6383
• Gene
  KNG1
• Long gene name
  kininogen 1
• Synonyms gene
  • KNG
  • BDK
• Synonyms gene name
  • kininogen
• Synonyms
  • BK
• Synonyms name
  • alpha-2-thiol proteinase inhibitor
  • bradykinin
• Locus
  3q27.3
• Discovery year
  1990-07-26
• Entrez gene record
  3827
• Pubmed identfication
  • 1733668
• RefSeq identity
  • NM_001102416
• Classification
  • Cystatins, type 3
  • Neuropeptides
• VEGA ID
  OTTHUMG00000150348
• Locus Specific Databases
  • LRG_598

Gene info

• Identity
  HGNC:31639
• Gene
  MIR7-2
• Long gene name
  microRNA 7-2
• Synonyms gene
  • MIRN7-2
• Synonyms
  • hsa-mir-7-2
• Locus
  15q26.1
• Discovery year
  2004-04-23
• Entrez gene record
  407044
• RefSeq identity
  • NR_029606
• Classification
  • MicroRNA MIR7 family

Gene info

• Identity
  HGNC:32051
• Gene
  MIR329-2
• Long gene name
  microRNA 329-2
• Synonyms gene
  • MIRN329-2
• Synonyms
  • hsa-mir-329-2
• Locus
  14q32.31
• Discovery year
  2005-07-11
• Entrez gene record
  574409
• RefSeq identity
  • NR_029968
• Classification
  • MicroRNA MIR329 family

Gene info

• Identity
  HGNC:32091
• Gene
  MIR512-2
• Long gene name
  microRNA 512-2
• Synonyms gene
  • MIRN512-2
• Synonyms
  • hsa-mir-512-2
• Locus
  19q13.42
• Discovery year
  2005-07-15
• Entrez gene record
  574459
• RefSeq identity
  • NR_030181
• Classification
  • MicroRNA MIR506 family

Gene info

• Identity
  HGNC:32113
• Gene
  MIR521-2
• Long gene name
  microRNA 521-2
• Synonyms gene
  • MIRN521-2
• Synonyms
  • hsa-mir-521-2
• Locus
  19q13.42
• Discovery year
  2005-07-15
• Entrez gene record
  574481
• RefSeq identity
  • NR_030203
• Classification
  • MicroRNA MIR515 family

Gene info

• Identity
  HGNC:35282
• Gene
  MIR1289-2
• Long gene name
  microRNA 1289-2
• Synonyms gene
  • MIRN1289-2
• Synonyms
  • hsa-mir-1289-2
• Locus
  5q31.1
• Discovery year
  2008-11-03
• Entrez gene record
  100302134
• RefSeq identity
  • NR_031621
• Classification
  • MicroRNA MIR1289 family

Gene info

• Identity
  HGNC:33641
• Gene
  MIR509-2
• Long gene name
  microRNA 509-2
• Synonyms gene
  • MIRN509-2
• Synonyms
  • hsa-mir-509-2
• Locus
  Xq27.3
• Discovery year
  2007-10-24
• Entrez gene record
  100126301
• RefSeq identity
  • NR_030586
• Classification
  • MicroRNA MIR506 family

Gene info

• Identity
  HGNC:18923
• Gene
  KRTAP13-2
• Long gene name
  keratin associated protein 13-2
• Synonyms
  • KAP13-2
• GenBank acession
  • AP001708
• Locus
  21q22.11
• Discovery year
  2003-02-21
• Entrez gene record
  337959
• Pubmed identfication
  • 12359730
• Classification
  • Keratin associated proteins
• VEGA ID
  OTTHUMG00000057793

Gene info

• Identity
  HGNC:34270
• Gene
  RNU6-2
• Long gene name
  RNA, U6 small nuclear 2
• Synonyms
  • U6-2
• Locus
  19p13.3
• Discovery year
  2008-06-10
• Entrez gene record
  103625684
• Pubmed identfication
  • 12711679
• RefSeq identity
  • NR_125730
• Classification
  • Small nuclear RNAs

Gene info

• Identity
  HGNC:33068
• Gene
  SNORD116-2
• Long gene name
  small nucleolar RNA, C/D box 116-2
• Synonyms
  • HBII-85-2
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033414
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003317
• Classification
  • Small nucleolar RNAs, C/D box

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