IRE1p, phosphorylated (Ser724) (Inositol-Requiring Protein 1, IRE1a, IRE1 alpha, Endoplasmic Reticulum-to-Nucleus Signaling 1, ERN1, FLJ30999, Serine/Threonine Protein Kinase/Endoribonuclease IRE1)
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Catalog number
MBS610146
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Price
Please ask
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Size
0.1 mL
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Products_type
Antibody
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Products_short_name
[IRE1p]
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Products_name_syn
[Anti -IRE1p, phosphorylated (Ser724) (Inositol-Requiring Protein 1, IRE1a, IRE1 alpha, Endoplasmic Reticulum-to-Nucleus Signaling 1, ERN1, FLJ30999, Serine/Threonine Protein Kinase/Endoribonuclease IRE1)]
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Other_names
[Ire1p; Serine/threonine-protein kinase/endoribonuclease IRE1; Ire1p; Endoplasmic reticulum-to-nucleus signaling 1]
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Other_gene_names
[IRE1; IRE1; ERN1; ERN1]
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Clonality
Polyclonal
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Reactivity
Human, Mouse, Rat
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Specificity
Recognizes human IRE1p, phosphorylated (Ser724) at~110kD. Species Crossreactivity: rat and mouse. Does not react with monkey.
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Purity
Affinity Purified Purified by immunoaffinity chromatography.
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Form
Supplied as a liquid in PBS, 0.1% sodium azide, 30% glycerol.
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Storage_stability
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested_application
Western Blot (WB)
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Description
The IRE1p, phosphorylated (Ser724) (Inositol-Requiring Protein 1, IRE1a, IRE1 alpha, Endoplasmic Reticulum- -Nucleus Signaling 1, ERN1, FLJ30999, Serine/Threonine Protein Kinase/Endoribonuclease IRE1) is a α- or alpha protein sometimes glycoprotein present in blood. Serine protease, D- or L-serine arginine rich enzyme of serine threonine kinase with serine that is encoded by the codons UCU, UCC, UCA, UCG, AGU and AGC is an ɑ-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH+
3 form under biological conditions), a carboxyl group. It is non-essential in humans, meaning the body can synthesize it. Cell nucleus signaling proteins and molecules are part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be created.
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Gene target
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Gene symbol
ERN1
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Short name
IRE1p, phosphorylated (Ser724) (Inositol-Requiring Protein 1, IRE1a, IRE1 alpha, Endoplasmic Reticulum- -Nucleus Signaling 1, ERN1, FLJ30999, Serine/Threonine Protein Kinase/Endoribonuclease IRE1)
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Host
Rabbit
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Isotype
IgG
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Alternative name
IRE1p, phosphorylated (Ser724) (Inositol-Requiring Protein 1, IRE1a, IRE1 a, Endoplasmic Reticulum-to-Nucleus Signaling 1, endoplasmic reticulum to nucleus signaling 1, FLJ30999, Serine/Threonine Protein phosphorylation catalyst/Endoribonuclease IRE1)
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Alternative to gene target
endoplasmic reticulum to nucleus signaling 1, hIRE1p and IRE1 and IRE1a and IRE1P, ERN1 and IDBG-64539 and ENSG00000178607 and 2081, transferase activity, nuclei, Ern1 and IDBG-213476 and ENSMUSG00000020715 and 78943, ERN1 and IDBG-641835 and ENSBTAG00000016799 and 524719
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Gene info
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