Interleukin 4, Recombinant, Mouse (Interleukin-4, IL-4, IL4, B-cell Stimulatory Factor 1, BSF-1, Lymphocyte Stimulatory Factor 1)
-
Catalog numberMBS650334
-
PricePlease ask
-
Size0.01 mg
-
-
Products_typeActive Protein
-
Products_short_name[Interleukin 4, Recombinant, Mouse]
-
Products_name_syn[Interleukin-4; IL-4; IL4; B-cell Stimulatory Factor 1; BSF-1; Lymphocyte Stimulatory Factor 1]
-
Other_names[interleukin 4; interleukin 4; interleukin-4; interleukin 4]
-
Other_gene_names[il4; bsf1; il-4; bcgf1; bcgf-1]
-
ReactivityMouse
-
Purity~98% (SDS-PAGE, reduced and non-reduced). Endotoxin: 0.01ng/1ug. (~98% (SDS-PAGE, reduced and non-reduced). Endotoxin: 0.01ng/1ug).
-
FormSupplied as a lyophilized powder from a 0.22um filtered solution of PBS, pH 7.2.
-
Storage_stabilityLyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.Shipping Temperature: Blue Ice
-
Tested_applicationWestern Blot
-
DescriptionFor cells, cell lines and tissues in culture till half confluency. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
-
GeneInterleukin 4 (IL4) is a cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. It is used for dendritic and T cell therapy. Upon activation by IL-4, Th2 cells subsequently produce additional IL-4 in a positive feedback loop. The cell that initially produces IL-4, thus inducing Th0 differentiation, has not been identified, but recent studies suggest that basophils may be the effector cell. It is closely related and has functions similar to Interleukin 13. Recombinant, GMP rec. E. coli interleukin-4 for cell culture supplied by GENTAUR. Free samples on request.
-
TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
-
Latin nameMus musculus
-
SourceRecombinants or rec. proteins
-
Grouprecombinants
-
Gene target
-
Gene symbolIL4, STAT6, IGHV7-4-1, IL19, IL17F, IL36G, CLCF1, TRV-CAC1-4, TRQ-CTG1-4, IL25
-
Short nameInterleukin 4, Recombinant, Mouse (Interleukin-4, IL-4, IL4, B- Stimulatory Factor 1, BSF-1, Lymphocyte Stimulatory Factor 1)
-
TechniqueRecombinant, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
-
HostHuman 293 Cells
-
SpeciesMouse, Mouses
-
Alternative nameInterleukin 4, Rec., Mouse (Interleukin-4, Interleukin-4, interleukin 4, B-cellular Stimulatory Factor 1, BSF-1, Lymphocyte Stimulatory Factor 1)
-
Alternative techniquerec, murine
-
Alternative to gene targetinterleukin 4, BCGF-1 and BCGF1 and BSF-1 and BSF1 and IL-4, IL4 and IDBG-42701 and ENSG00000113520 and 3565, growth factor activity, Extracellular, Il4 and IDBG-172024 and ENSMUSG00000000869 and 16189, IL4 and IDBG-644671 and ENSBTAG00000015957 and 280824
-
Tissuecell, lymphocyte
-
Gene info
-
Identity
-
Gene
-
Long gene nameinterleukin 4
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1988-08-10
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Interleukins
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namesignal transducer and activator of transcription 6
-
Synonyms gene name
- signal transducer and activator of transcription 6, interleukin-4 induced
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1995-11-09
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- SH2 domain containing
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene nameimmunoglobulin heavy variable 7-4-1
-
GenBank acession
-
Locus
-
Discovery year2000-04-04
-
Entrez gene record
-
RefSeq identity
-
Classification
- Immunoglobulin heavy locus at 14q32.33
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameinterleukin 19
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2000-03-29
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Interleukins
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameinterleukin 17F
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2002-03-18
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Interleukins
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene nameinterleukin 36 gamma
-
Synonyms gene
-
Synonyms gene name
- interleukin 1 family, member 9
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2002-08-02
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Interleukins
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namecardiotrophin like cytokine factor 1
-
Synonyms gene name
- CRLF1 associated cytokine-like factor 1
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2005-02-22
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Interleukin 6 type cytokine family
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nametRNA-Val (anticodon CAC) 1-4
-
Synonyms gene
-
Synonyms gene name
- transfer RNA valine 4 (anticodon CAC)
- transfer RNA-Val (CAC) 1-4
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2008-08-27
-
Entrez gene record
-
Classification
- Cytoplasmic transfer RNAs
Gene info
-
Identity
-
Gene
-
Long gene nametRNA-Gln (anticodon CTG) 1-4
-
Synonyms gene
-
Synonyms gene name
- transfer RNA glutamine 24 (anticodon CUG)
- transfer RNA-Gln (CTG) 1-1
- transfer RNA-Gln (CTG) 1-4
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2008-08-29
-
Entrez gene record
-
Classification
- Cytoplasmic transfer RNAs
Gene info
-
Identity
-
Gene
-
Long gene nameinterleukin 25
-
Synonyms gene
-
Synonyms gene name
- interleukin 17E
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2001-01-26
-
Pubmed identfication
-
Classification
- Interleukins
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
-
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data