Interleukin-1 receptor type 1

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Description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

Identity

HGNC:5993
Gene

IL1R1
Long gene name

interleukin 1 receptor type 1
Synonyms gene
- IL1R
- IL1RA
Synonyms gene name
- interleukin 1 receptor, type I
Synonyms
- D2S1473
- CD121A
Synonyms name
- interleukin-1 receptor, type I
GenBank acession
- M27492
Locus

2q11.2-q12.1
Discovery year

1990-06-27
Entrez gene record

3554
Pubmed identfication
- 1833184
- 10191101
Classification
- I-set domain containing
- Interleukin receptors
- TIR domain containing
- CD molecules
VEGA ID

OTTHUMG00000130783