Integrin, beta1 (Integrin beta-1, ITGB1, CD29, Fibronectin Receptor Subunit beta, FNRB, GPIIA, MDF2, MSK12, VLA-4 Subunit beta, VLA-BETA, VLAB)

• Catalog number
  MBS609806
• Price
  Please ask
• Size
  1 mL

• Products_type
  Antibody
• Products_short_name
  [Integrin, beta1]
• Products_name_syn
  [Anti -Integrin, beta1 (Integrin beta-1, ITGB1, CD29, Fibronectin Receptor Subunit beta, FNRB, GPIIA, MDF2, MSK12, VLA-4 Subunit beta, VLA-BETA, VLAB)]
• Other_names
  [integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); Integrin, beta 1 (Fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); integrin beta-1; OTTHUMP00000019420; integrin VLA-4 beta subunit; very late activation protein, beta polypeptide; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)]
• Other_gene_names
  [ITGB1; ITGB1; CD29; FNRB; MDF2; VLAB; GPIIA; MSK12; VLA-BETA]
• Clonality
  Monoclonal
• Clone
  [BV7]
• Reactivity
  Human
• Specificity
  Recognizes human b1-integrin chain present on tumor cells. Active on HT-29 colon carcicoma cells and on HCCP-2998 tumor cells and binds to several other tumor cells (MG3 osteosarcoma, A375 melanoma, MHCC-1410 and Lovo colon carcinoma) but does not affect adhesion to endothelial cells.
• Purity
  Purified Purified
• Form
  Supplied as a liquid in PBS, 0.1% BSA.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Integrin   beta1   Integrin   beta-1   ITGB1   CD29   Fibronectin   Receptor   Subunit   beta   FNRB   GPIIA   MDF2   MSK12   VLA-4   Subunit   beta   VLA-BETA   VLAB  
• Gene symbol
  ITGB1, AP4B1, ITGB1-DT, TUBB3, IATPR, KCNMB1, DNAJC5B, NAPB, MIR1302-4, GPR63
• Short name
  Integrin, beta1 (Integrin beta-1, ITGB1, CD29, Fibronectin Receptor Subunit beta, FNRB, GPIIA, MDF2, MSK12, VLA-4 Subunit beta, VLA-BETA, VLAB)
• Host
  Mouse
• Isotype
  IgG1
• Alternative name
  Integrin, beta1 (Integrin b-1, integrin, b 1 (fibronectin receptor, b polypeptide, antigen CD29 includes MDF2, MSK12), CD29, Fibronectin Receptor functionnal sequence b, FNRB, GPIIA, MDF2, MSK12, VLA-4 functionnal sequence b, VLA-b, VLAB)
• Alternative to gene target
  integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12), CD29 and FNRB and GPIIA and MDF2 and MSK12 and VLA-BETA and VLAB, ITGB1 and IDBG-68302 and ENSG00000150093 and 3688, alpha-actinin binding, Cell surfaces, Itgb1 and IDBG-201159 and ENSMUSG00000025809 and 16412, ITGB1 and IDBG-637396 and ENSBTAG00000015910 and 281876

Gene info

• Identity
  HGNC:6153
• Gene
  ITGB1
• Long gene name
  integrin subunit beta 1
• Synonyms gene
  • FNRB
  • MSK12
  • MDF2
• Synonyms gene name
  • integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
• Synonyms
  • CD29
  • GPIIA
• GenBank acession
  • BC020057
• Locus
  10p11.22
• Discovery year
  1988-06-27
• Entrez gene record
  3688
• Pubmed identfication
  • 2524991
• RefSeq identity
  • NM_002211
• Classification
  • CD molecules
  • Integrin beta subunits
• VEGA ID
  OTTHUMG00000017928

Gene info

• Identity
  HGNC:572
• Gene
  AP4B1
• Long gene name
  adaptor related protein complex 4 subunit beta 1
• Synonyms gene
  • SPG47
• Synonyms gene name
  • spastic paraplegia 47
  • adaptor related protein complex 4 beta 1 subunit
• Synonyms
  • BETA-4
• Synonyms name
  • beta 4 subunit of AP-4
  • AP-4 complex subunit beta-1
• GenBank acession
  • AF092094
• Locus
  1p13.2
• Discovery year
  2000-09-01
• Entrez gene record
  10717
• Pubmed identfication
  • 10066790
• RefSeq identity
  • NM_006594
• Classification
  • Adaptor related protein complex 4
  • Clathrin/coatomer adaptor, adaptin-like, N-terminal domain containing
• VEGA ID
  OTTHUMG00000011943

Gene info

• Identity
  HGNC:53718
• Gene
  ITGB1-DT
• Long gene name
  ITGB1 divergent transcript
• Locus
  10p11.22
• Discovery year
  2017-09-01
• Entrez gene record
  101929475
• Classification
  • Divergent transcripts

Gene info

• Identity
  HGNC:20772
• Gene
  TUBB3
• Long gene name
  tubulin beta 3 class III
• Synonyms gene
  • FEOM3
• Synonyms gene name
  • tubulin, beta 3
  • fibrosis of extraocular muscles, congenital, 3
• Synonyms
  • beta-4
  • CFEOM3
  • CFEOM3A
• Synonyms name
  • class III beta-tubulin
• GenBank acession
  • BC000748
• Locus
  16q24.3
• Discovery year
  2004-11-22
• Entrez gene record
  10381
• Pubmed identfication
  • 9473684
  • 8098743
  • 20074521
• RefSeq identity
  • NM_006086
• Classification
  • Tubulins
• VEGA ID
  OTTHUMG00000138985

Gene info

• Identity
  HGNC:53719
• Gene
  IATPR
• Long gene name
  ITGB1 adjacent tumor promoting lncRNA
• Synonyms
  • TCONS_00018476
  • linc-ITGB1
• Locus
  10p11.22
• Discovery year
  2018-08-22
• Entrez gene record
  101929447
• Pubmed identfication
  • 28829502
  • 26601916
  • 25893892
• Classification
  • Long non-coding RNAs with non-systematic symbols

Gene info

• Identity
  HGNC:6285
• Gene
  KCNMB1
• Long gene name
  potassium calcium-activated channel subfamily M regulatory beta subunit 1
• Synonyms gene name
  • potassium large conductance calcium-activated channel, subfamily M, beta member 1
  • potassium channel subfamily M regulatory beta subunit 1
• Synonyms
  • hslo-beta
• Synonyms name
  • BK channel beta subunit 1
  • MaxiK channel beta-subunit 1
  • big potassium channel beta subunit 1
• GenBank acession
  • AF035046
• Locus
  5q35.1
• Discovery year
  1997-12-05
• Entrez gene record
  3779
• Pubmed identfication
  • 8799178
  • 9888999
• Classification
  • Potassium calcium-activated channel subfamily M regulatory beta subunits
• VEGA ID
  OTTHUMG00000130439

Gene info

• Identity
  HGNC:24138
• Gene
  DNAJC5B
• Long gene name
  DnaJ heat shock protein family (Hsp40) member C5 beta
• Synonyms gene name
  • DnaJ (Hsp40) homolog, subfamily C, member 5 beta
• Synonyms
  • MGC26226
  • CSP-beta
• GenBank acession
  • AF368276
• Locus
  8q13.1
• Discovery year
  2004-03-16
• Entrez gene record
  85479
• Pubmed identfication
  • 29182667
• RefSeq identity
  • NM_033105
• Classification
  • DNAJ (HSP40) heat shock proteins
• VEGA ID
  OTTHUMG00000164470

Gene info

• Identity
  HGNC:15751
• Gene
  NAPB
• Long gene name
  NSF attachment protein beta
• Synonyms gene name
  • N-ethylmaleimide-sensitive factor attachment protein, beta
• Synonyms
  • SNAP-BETA
  • SNAPB
• Synonyms name
  • beta soluble NSF attachment protein
• GenBank acession
  • AK022817
• Locus
  20p11.21
• Discovery year
  2001-05-30
• Entrez gene record
  63908
• Pubmed identfication
  • 8455721
• RefSeq identity
  • NM_022080
• VEGA ID
  OTTHUMG00000032062

Gene info

• Identity
  HGNC:35296
• Gene
  MIR1302-4
• Long gene name
  microRNA 1302-4
• Synonyms gene
  • MIRN1302-4
• Synonyms
  • hsa-mir-1302-4
• Locus
  2q33.3
• Discovery year
  2008-11-03
• Entrez gene record
  100302130
• RefSeq identity
  • NR_031633
• Classification
  • MicroRNA MIR1302 family

Gene info

• Identity
  HGNC:13302
• Gene
  GPR63
• Long gene name
  G protein-coupled receptor 63
• Synonyms
  • PSP24(beta)
  • PSP24B
• GenBank acession
  • AF317654
• Locus
  6q16.1
• Discovery year
  2001-04-05
• Entrez gene record
  81491
• Classification
  • G protein-coupled receptors, Class A orphans
• VEGA ID
  OTTHUMG00000015245

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