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Products_type
Antibody
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Products_short_name
[Integrin alpha2, beta1]
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Products_name_syn
[Anti -Integrin alpha2, beta1 (Collagen Receptor, VLA2)]
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Other_names
[integrin alpha-3 isoform b; Integrin alpha-3; integrin alpha-3; FRP-2; galactoprotein B3; VLA-3 subunit alpha; CD49 antigen-like family member C; antigen identified by monoclonal antibody J143; very late activation protein 3 receptor, alpha-3 subunit; integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor); CD49 antigen-like family member C; FRP-2; Galactoprotein B3; GAPB3; VLA-3 subunit alpha]
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Other_gene_names
[ITGA3; ITGA3; VL3A; CD49C; GAPB3; ILNEB; MSK18; VCA-2; VLA3a; GAP-B3; MSK18; GAPB3]
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Clonality
Monoclonal
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Clone
[2Q1003]
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Reactivity
Human, Porcine
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Specificity
Recognizes the human collagen receptor VLA-2 (alpha 2 beta 1) integrin complex. Species Crossreactivity: porcine
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Purity
Affinity Purified Purified by Protein A affinity chromatography.
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Form
Supplied as a liquid in PBS, pH 7.6, 0.1% sodium azide.
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Storage_stability
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested_application
Immunoprecipitation (IP), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
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Gene
Collagen Types in bones and muscles can be hydrolyzed and used in human grafts. ( Type II )
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
