IgE, Kappa, Human (non-immune)

• Catalog number
  MBS655060
• Price
  4440.89 USD
• Size
  5x0.1 mL

• Products_type
  Immunoglobulin
• Products_short_name
  [IgE, Kappa]
• Purity
  Affinity Purified Purified by Protein L affinity chromatography. The purity of the human IgE is > 98%, tested by SDS-PAGE.
• Form
  Supplied as a liquid in 0.01M phosphate buffer, pH 7.4, 0.15M sodium chloride.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested_application
  ELISA (EL/EIA), Immunohistochemistry (IHC)
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples. Immunoglobulin E (IgE) kappa or Fc specific antibody is a kind of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals. IgE is synthesized by plasma cells. Monomers of IgE consist of two heavy chains (ε chain) and two light chains, with the ε chain containing 4 Ig-like constant domains (Cε1-Cε4). IgEs play a role in allergy and response to parasite infection. High levels of IgEs caused by parasites can lower the allergic reaction of patients to allergens common present in the human environment. As such the parasite history of an allergic patient needs to be taken in consideration as a positive factor.
• Description
  Complexes, systems, regulators, immune RNAs and non immune controls that can react with a specific antigen epitope.

• Gene target
  Kappa   non  
• Gene symbol
  IGKV6D-41, IGKV2D-24, IGKV1D-42
• Short name
  IgE, Kappa, (non-immune)
• Technique
  immune, IgE, IgEs, immuno
• Isotype
  IgE,k, IgE
• Species
  Human, Humans
• Alternative name
  immunoglobuline E, Kappa, H. sapiens (non-immune)
• Alternative technique
  immuno, immunoglobulin-e

Gene info

• Identity
  HGNC:5838
• Gene
  IGKV6D-41
• Long gene name
  immunoglobulin kappa variable 6D-41 (non-functional)
• Synonyms gene name
  • immunoglobulin kappa variable 6D-41
• GenBank acession
  • X12688
• Locus
  2p11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28869
• RefSeq identity
  • NG_000833
• Classification
  • Immunoglobulin kappa locus at 2p11.2
• VEGA ID
  OTTHUMG00000151621

Gene info

• Identity
  HGNC:5797
• Gene
  IGKV2D-24
• Long gene name
  immunoglobulin kappa variable 2D-24 (non-functional)
• Synonyms gene name
  • immunoglobulin kappa variable 2D-24
• GenBank acession
  • X63401
• Locus
  2p11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28885
• RefSeq identity
  • NG_000833
• Classification
  • Immunoglobulin kappa locus at 2p11.2
• VEGA ID
  OTTHUMG00000151618

Gene info

• Identity
  HGNC:5757
• Gene
  IGKV1D-42
• Long gene name
  immunoglobulin kappa variable 1D-42 (non-functional)
• Synonyms gene name
  • immunoglobulin kappa variable 1D-42
• GenBank acession
  • X72816
• Locus
  2p11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28892
• RefSeq identity
  • NG_000833
• Classification
  • Immunoglobulin kappa locus at 2p11.2
• VEGA ID
  OTTHUMG00000151573

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