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Products_type
Active Protein
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Products_short_name
[TWEAK Receptor]
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Products_name_syn
[Recombinant Human TWEAK Receptor]
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Other_names
[Tumor necrosis factor receptor superfamily member 12A; Tumor necrosis factor receptor superfamily member 12A; tumor necrosis factor receptor superfamily member 12A; tweak-receptor; FGF-inducible 14; type I transmembrane protein Fn14; fibroblast growth factor-inducible immediate-early response protein 14; tumor necrosis factor receptor superfamily, member 12A; Fibroblast growth factor-inducible immediate-early response protein 14; FGF-inducible 14; Tweak-receptor; TweakR; CD_antigen: CD266]
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Products_gene_name
[TWEAK]
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Other_gene_names
[TNFRSF12A; TNFRSF12A; FN14; CD266; TWEAKR; FN14; FGF-inducible 14; TweakR]
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Reactivity
Species Reactivity: Human
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Purity
Above 98% as determined by SDS-PAGE Analysis.
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Storage_stability
At -20 degree C
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
