Human PAI-1 Stable Mutant, Low Endotoxin

Products_type

Recombinant Protein
Products_short_name

[PAI-1 Stable Mutant]
Other_names

[plasminogen activator inhibitor 1; Plasminogen activator inhibitor 1; plasminogen activator inhibitor 1; serpin family E member 1; Endothelial plasminogen activator inhibitor; Serpin E1]
Products_gene_name

[SERPINE1]
Other_gene_names

[SERPINE1; SERPINE1; PAI; PAI1; PAI-1; PLANH1; PAI1; PLANH1; PAI; PAI-1]
Purity

>95% by SDS-PAGE analysis
Form

Lyophilized powder0.0067M Phosphate; 0.15M NaCl; pH 7.4
Storage_stability

Store at -20 degree CExpiration: 3 years from deliveryShipping: Cold pack
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Gene

Plasminogen activator inhibitor-1 (PAI-1) also known as endothelial plasminogen activator inhibitor or serpin E1 is a protein that in humans is encoded by the SERPINE1 gene. Elevated PAI-1 is a risk factor for thrombosis and atherosclerosis

Gene target

PAI-1 Stable Mutant Endotoxin
Gene symbol

SERPINE1, SERPINB2, SERBP1, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR1289-1, MIR101-1
Short name

PAI-1 Stable Mutant, Endotoxin
Host

E Coli
Species

Human, Humans
Alternative name

H. sapiens PAI-1 Stable Mutant, Low Endotoxin

Identity

HGNC:8583
Gene

SERPINE1
Long gene name

serpin family E member 1
Synonyms gene
- PLANH1
- PAI1
Synonyms gene name
- serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Synonyms
- PAI
Synonyms name
- plasminogen activator inhibitor, type I
GenBank acession
- M16006
Locus

7q22.1
Discovery year

1986-01-01
Entrez gene record

5054
Pubmed identfication
- 3097076
- 2891140
- 24172014
RefSeq identity
- NM_000602
Classification
- Serpin peptidase inhibitors
VEGA ID

OTTHUMG00000157107
Locus Specific Databases
- LRG_597

Identity

HGNC:8584
Gene

SERPINB2
Long gene name

serpin family B member 2
Synonyms gene
- PLANH2
- PAI2
Synonyms gene name
- serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2
- serpin peptidase inhibitor, clade B (ovalbumin), member 2
Synonyms
- HsT1201
- PAI-2
Synonyms name
- plasminogen-activator inhibitor
GenBank acession
- Y00630
Locus

18q21.33-q22.1
Discovery year

1989-02-07
Entrez gene record

5055
Pubmed identfication
- 24172014
RefSeq identity
- NM_002575
Classification
- Serpin peptidase inhibitors
VEGA ID

OTTHUMG00000060592

Identity

HGNC:5670
Gene

IGHVII-1-1
Long gene name

immunoglobulin heavy variable (II)-1-1 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
Synonyms
- IGHV(II)-1-1
GenBank acession
- AB019441
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28377
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000152325

Identity

HGNC:5760
Gene

IGKV1OR2-1
Long gene name

immunoglobulin kappa variable 1/OR2-1 (pseudogene)
Synonyms gene
- IGKVPZ1
- IGKV1OR-1
Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
Synonyms
- IGKV1/OR-1
- IGKV1/OR2-1
GenBank acession
- Z12367
Locus

2p11.1
Discovery year

2000-04-18
Entrez gene record

3531
Pubmed identfication
- 2853098
Classification
- Immunoglobulin kappa (IGK) orphons
VEGA ID

OTTHUMG00000155081

Name

Limulus Test
Concept

Scope note: Sensitive method for detection of bacterial endotoxins and endotoxin-like substances that depends on the in vitro gelation of Limulus amebocyte lysate (LAL), prepared from the circulating blood (amebocytes) of the horseshoe crab, by the endotoxin or related compound. Used for detection of endotoxin in body fluids and parenteral pharmaceuticals.
Tree numbers
- E01.370.225.124.470
- E01.370.225.875.150.570
- E05.091.570
- E05.200.124.470
- E05.200.875.150.570
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data