Human leptin

• Catalog number
  MBS400030
• Price
  Please ask
• Size
  500 mg

• Products_type
  Active Protein
• Products_short_name
  [leptin]
• Products_name_syn
  [Human leptin]
• Other_names
  [leptin; Leptin; leptin; obesity factor; leptin; Obesity factor]
• Other_gene_names
  [Lep; Lep; OB; obese; Ob]
• Purity
  Purity of recombinant human leptin is greater than 98.0% as determined by:(a) Gel filtration analysis of the recombinant protein.(b) Analysis by reducing and non-reducing SDS-PAGE gel.
• Form
  White lyophilized (freeze-dried) powder.
• Storage_stability
  Lyophilized recombinant human leptin although stable at room temperature for several weeks, should be stored desiccated below -18 degree C. Upon reconstitution at > 0.1 human leptin mg/ml and up to 2 mg and filter sterilization recombinant human leptin can be stored at +4 degree C or even room temperature for several weeks. At lower concentration addition of a carrier protein (0.1% HSA or BSA) is suggested. Please prevent freeze-thaw cycles.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Gene
  Human or mouse Leptin (from Greek λεπτός leptos, "thin") the "satiety hormone", is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Leptin is opposed by the actions of the hormone ghrelin, the "hunger hormone". Both hormones act on receptors in the arcuate nucleus of the hypothalamus to regulate appetite to achieve energy homeostasis. ELISA kits and peptides and antibodies are available.

• Gene target
  leptin  
• Gene symbol
  LEP, LEPR, LEPROT
• Short name
  leptin
• Host
  Escherichia Coli
• Species
  Human, Humans
• Alternative name
  H. sapiens leptin

Gene info

• Identity
  HGNC:6553
• Gene
  LEP
• Long gene name
  leptin
• Synonyms gene
  • OBS
  • OB
• Synonyms gene name
  • leptin (murine obesity homolog)
  • leptin (obesity homolog, mouse)
• Locus
  7q32.1
• Discovery year
  1993-01-26
• Entrez gene record
  3952
• Pubmed identfication
  • 1686014
  • 16932309
• Classification
  • Neuropeptides
• VEGA ID
  OTTHUMG00000157564

Gene info

• Identity
  HGNC:6554
• Gene
  LEPR
• Long gene name
  leptin receptor
• Synonyms
  • OBR
  • CD295
• GenBank acession
  • U43168
• Locus
  1p31.3
• Discovery year
  1996-05-09
• Entrez gene record
  3953
• Pubmed identfication
  • 8548812
  • 8812446
• RefSeq identity
  • NM_002303
• Classification
  • CD molecules
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000009115
• Locus Specific Databases
  • LRG_283

Gene info

• Identity
  HGNC:29477
• Gene
  LEPROT
• Long gene name
  leptin receptor overlapping transcript
• Synonyms
  • OBRGRP
  • OB-RGRP
  • VPS55
  • FLJ90360
• Synonyms name
  • leptin receptor gene related protein
  • endospanin-1
  • endospanin
• GenBank acession
  • Y12670
• Locus
  1p31.3
• Discovery year
  2004-11-16
• Entrez gene record
  54741
• Pubmed identfication
  • 9207021
  • 21454707
• RefSeq identity
  • NM_017526
• VEGA ID
  OTTHUMG00000009065

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