Human IL8 (77aa Residues) (Interleukin 8) Recombinant Protein Without Tag

• Catalog number
  MBS698079
• Price
  Please ask
• Size
  5x1 mg

• Products_type
  Recombinant Protein
• Products_short_name
  [IL8 (Interleukin 8)]
• Products_name_syn
  [Interleukin 8 (77aa); Small inducible cytokine subfamily B; member 8; SCYB8; Monocyte-derived neutrophil chemotactic factor; Neutrophil-activating peptide 1; NAP1 Granulocyte chemotactic protein 1; GCP1; CXC chemokine ligand 8; CXCL11]
• Other_names
  [interleukin-8 isoform 1; Interleukin-8; interleukin-8; C-X-C motif chemokine ligand 8; C-X-C motif chemokine 8; Emoctakin; Granulocyte chemotactic protein 1; GCP-1; Monocyte-derived neutrophil chemotactic factor; MDNCF; Monocyte-derived neutrophil-activating peptide; MONAP; Neutrophil-activating protein 1; NAP-1; Protein 3-10C; T-cell chemotactic factorCleaved into the following 7 chains:MDNCF-a; Alternative name(s):; GCP/IL-8 protein IV; IL8/NAP1 form IInterleukin-8; Alternative name(s):; (Ala-IL-8)77; GCP/IL-8 protein II; IL-8(1-77); IL8/NAP1 form II; MDNCF-bIL-8(5-77)IL-8(6-77); Alternative name(s):; (Ser-IL-8)72; GCP/IL-8 protein I; IL8/NAP1 form III; Lymphocyte-derived neutrophil-activating factor; LYNAP; MDNCF-c; Neutrophil-activating factor; NAFIL-8(7-77); Alternative name(s):; GCP/IL-8 protein V; IL8/NAP1 form IVIL-8(8-77); Alternative name(s):; GCP/IL-8 protein VI; IL8/NAP1 form VIL-8(9-77); Alternative name(s):; GCP/IL-8 protein III; IL8/NAP1 form VI]
• Products_gene_name
  [IL8]
• Other_gene_names
  [CXCL8; IL8; IL8; NAF; GCP1; LECT; LUCT; NAP1; GCP-1; LYNAP; MDNCF; MONAP; NAP-1; SCYB8; CXCL8; IL-8; GCP-1; MDNCF; MONAP; NAP-1; LYNAP; NAF]
• Purity
  >95%Purification: 6xHis tag, Immobilized-metal affinity chromatography (IMAC) + TEV protease cleavage of the tag
• Form
  Lyophilized from a solution containing TrisHCl 50mM pH 8.0 and 0.5mM EDTA and 1mM DTT
• Storage_stability
  Prior to reconstitution, store the lyophilized protein at 2-8 degree C. After reconstitution, store in working aliquots at -80 degree C.
• Tested_application
  ELISA (EIA), Western Blot (WB), Antibody Production, Protein Array
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Gene
  Interleukin 8 (IL8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells and endothelial cells. Endothelial cells store IL-8 in their storage vesicles, the Weibel-Palade bodies. In humans, the interleukin-8 proteins encoded by the IL8 gene. IL-8 is initially produced as a precursor peptide of 99 amino acids long which then undergoes cleavage to create several active IL-8 isoforms. In culture, a 72 amino acid peptide is the major form secreted by macrophages. Recombinant, rec. E. coli interleukin-8 for cell culture or antibody production.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  IL8   77aa   Residues   Interleukin   Protein   Without   Tag  
• Gene symbol
  CXCL8
• Short name
  IL8 (77aa Residues) (Interleukin 8) Recombinant Protein Without Tag
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Host
  E Coli
• Label
  tag
• Species
  Human, Humans
• Alternative name
  H. sapiens interleukin 8 (77aa Residues) (Interleukin 8) Rec. Protein Without detection labelled
• Alternative technique
  rec
• Alternative to gene target
  interleukin 8, GCP-1 and GCP1 and IL8 and LECT and LUCT and LYNAP and MDNCF and MONAP and NAF and NAP-1 and NAP1, IL8 and IDBG-23954 and ENSG00000169429 and 3576, chemokine activity, Extracellular, IL8 and IDBG-643010 and ENSBTAG00000019716 and 280828

Gene info

• Identity
  HGNC:6025
• Gene
  CXCL8
• Long gene name
  C-X-C motif chemokine ligand 8
• Synonyms gene
  • IL8
• Synonyms gene name
  • interleukin 8
  • chemokine (C-X-C motif) ligand 8
• Synonyms
  • SCYB8
  • LUCT
  • LECT
  • MDNCF
  • TSG-1
  • IL-8
  • NAP-1
  • 3-10C
  • MONAP
  • AMCF-I
  • LYNAP
  • NAF
  • b-ENAP
  • GCP-1
  • K60
  • GCP1
  • NAP1
• Synonyms name
  • neutrophil-activating peptide 1
  • granulocyte chemotactic protein 1
  • monocyte-derived neutrophil chemotactic factor
  • lung giant cell carcinoma-derived chemotactic protein
  • tumor necrosis factor-induced gene 1
  • monocyte-derived neutrophil-activating peptide
  • lymphocyte derived neutrophil activating peptide
  • beta endothelial cell-derived neutrophil activating peptide
  • alveolar macrophage chemotactic factor I
• GenBank acession
  • Y00787
• Locus
  4q13.3
• Discovery year
  1989-06-30
• Entrez gene record
  3576
• Pubmed identfication
  • 1427896
  • 11178128
• RefSeq identity
  • NM_000584
• Classification
  • Chemokine ligands
  • Interleukins
• VEGA ID
  OTTHUMG00000151316

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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