Human IgE Receptor

• Catalog number
  MBS596152
• Price
  821.02 USD
• Size
  2 mg

• Products_type
  Recombinant Protein
• Products_short_name
  [IgE]
• Other_names
  [immunoglobulin epsilon chain]
• Products_gene_name
  [IgE]
• Tested_application
  ELISA (EIA), Western Blot (WB)
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples. Immunoglobulin E (IgE) kappa or Fc specific antibody is a kind of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals. IgE is synthesized by plasma cells. Monomers of IgE consist of two heavy chains (ε chain) and two light chains, with the ε chain containing 4 Ig-like constant domains (Cε1-Cε4). IgEs play a role in allergy and response to parasite infection. High levels of IgEs caused by parasites can lower the allergic reaction of patients to allergens common present in the human environment. As such the parasite history of an allergic patient needs to be taken in consideration as a positive factor.
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Receptor  
• Gene symbol
  TACR3, CALCRL, OPRL1
• Short name
  IgE Receptor
• Technique
  IgE, IgEs
• Isotype
  IgE, IgE
• Species
  Human, Humans
• Alternative name
  H. sapiens immunoglobuline E Receptor
• Alternative technique
  immunoglobulin-e

Gene info

• Identity
  HGNC:11528
• Gene
  TACR3
• Long gene name
  tachykinin receptor 3
• Synonyms
  • NK3R
  • NKR
  • TAC3R
• Synonyms name
  • neurokinin beta receptor
  • neuromedin-K receptor
  • neurokinin B receptor
  • NK3 receptor
• GenBank acession
  • M89473
• Locus
  4q24
• Discovery year
  1997-11-28
• Entrez gene record
  6870
• Pubmed identfication
  • 1374246
  • 19079066
• RefSeq identity
  • NM_001059
• Classification
  • Tachykinin receptors
• VEGA ID
  OTTHUMG00000131124

Gene info

• Identity
  HGNC:16709
• Gene
  CALCRL
• Long gene name
  calcitonin receptor like receptor
• Synonyms gene name
  • calcitonin receptor-like
• Synonyms
  • CGRPR
  • CRLR
• GenBank acession
  • U17473
• Locus
  2q32.1
• Discovery year
  2001-10-02
• Entrez gene record
  10203
• Pubmed identfication
  • 7818539
  • 8626685
• RefSeq identity
  • NM_005795
• Classification
  • Calcitonin receptors
• VEGA ID
  OTTHUMG00000132636

Gene info

• Identity
  HGNC:8155
• Gene
  OPRL1
• Long gene name
  opioid related nociceptin receptor 1
• Synonyms gene name
  • opiate receptor-like 1
• Synonyms
  • NOCIR
  • ORL1
  • OOR
  • KOR-3
  • NOPr
  • PNOCR
• Synonyms name
  • LC132 receptor-like
  • orphanin FQ receptor
  • kappa3-related opioid receptor
  • nociceptin/orphanin FQ receptor
• Locus
  20q13.33
• Discovery year
  1996-05-28
• Entrez gene record
  4987
• Pubmed identfication
  • 8137918
  • 17910740
• RefSeq identity
  • NM_182647
• Classification
  • Opioid receptors
• VEGA ID
  OTTHUMG00000033027

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