Human growth hormone soluble receptor (hGH binding protein)
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Catalog number
MBS400018
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Price
Please ask
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Size
0.5 mg
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Products_type
Active Protein
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Products_short_name
[growth hormone soluble receptor]
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Products_name_syn
[Human growth hormone soluble receptor (so called hGH binding protein)]
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Other_names
[Growth hormone receptor; Growth hormone receptor; growth hormone receptor; GH receptor; growth hormone binding protein; serum binding protein; somatotropin receptor; growth hormone receptor; Somatotropin receptor]
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Other_gene_names
[GHR; GHR; GHBP; GHIP; GH receptor; GH-binding protein; GHBP]
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Purity
Greater than 95.0% as determined by:(a) Gel filtration analysis.(b) Analysis by reducing and non-reducing SDS-PAGE gel.
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Form
White lyophilized (freeze-dried) powder.
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Storage_stability
Lyophilized hGHBP although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution at > 0.1 hGHBP mg/ml and filter sterilization hGHBP can be stored at 4 degree C for several weeks. At lower concentration addition of a carrier protein (0.1% HSA or BSA) is suggested. Please prevent freeze-thaw cycles.
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Description
Hormone releasing factors and releasing hormones are signaling molecules produced by glands in multicellular organisms. The glands that secrete Luteinizing hormones LHRG and LH, FSH comprise the endocrine signaling system. The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signaling) or nearby cells (paracrine signaling). Human recombinant LHRG and GHRH are produced in E. coli or in yeast cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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