Human granulocyte macrophage-colony stimul. factor (GM-CSF)

  • Catalog number
    MBS400010
  • Price
    Please ask
  • Size
    0.1 mg
  • Products_type
    Active Protein
  • Products_short_name
    [granulocyte macrophage-colony stimul. factor]
  • Products_name_syn
    [Human Granulocyte Macrophage Colony Stimulating Factor (hGM-CSF)]
  • Other_names
    [Granulocyte-macrophage colony-stimulating factor; Granulocyte-macrophage colony-stimulating factor; granulocyte-macrophage colony-stimulating factor; CSF; granulocyte macrophage-colony stimulating factor; molgramostin; sargramostim; colony stimulating factor 2 (granulocyte-macrophage); Colony-stimulating factor; CSF; Molgramostin; Sargramostim]
  • Products_gene_name
    [GM-CSF]
  • Products_gene_name_syn
    [hGM-CSF]
  • Other_gene_names
    [CSF2; CSF2; GMCSF; GMCSF; GM-CSF; CSF]
  • Purity
    Greater than 98.0% as determined by:(a) Analysis by RP-HPLC.(b) Anion-exchange FPLC.(c) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel.(d) gel filtration on Superdex 75 column.
  • Form
    Sterile Filtered White lyophilized (freeze-dried) powder.
  • Storage_stability
    Lyophilized GM-CSF although stable at room temperature for 3 weeks, should be stored desiccated below -180 degree C. Upon reconstitution GM-CSF should be sterilized and stored at 4 degree C up to 7 days and for future use below -180 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze-thaw cycles.
  • Description
    Colonies can be formed by stimulating factors or recombinant GM-CSF and CSFs activity expressed in Units compared to a standard. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
  • Gene
    Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, NK cells, endothelial cells and fibroblasts that functions as a cytokine. The pharmaceutical analogs of naturally occurring GM-CSF are called sargramostim and molgramostim. Reconstitution It is recommended that sterile ddH2O containing at least 0.1% human serum albumin or bovine serum albumin be added to the vial to prepare a stock solution of not less than 1 mg/mL of the cytokine.
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Gene target
  • Gene symbol
    CSF2, PPP1R3A, CSF1, CSF3, IL3
  • Short name
    granulocyte macrophage-colony stimul. factor (GM-CSF)
  • Host
    E Coli
  • Species
    Human, Humans
  • Alternative name
    H. sapiens granulocyte macrophage-colony stimul. factor (GM-CSF)
  • Tissue
    granulocyte
Gene info
Gene info
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: A cytologic technique for measuring the functional capacity of stem cells by assaying their activity.
  • Tree numbers
    • E01.370.225.500.383
    • E05.200.500.383
    • E05.242.383
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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