Human Coagulation Factor VIII

• Catalog number
  MBS142873
• Price
  Please ask
• Size
  600 IU

• Products_type
  Active Protein
• Products_short_name
  [Coagulation Factor VIII]
• Products_name_syn
  [F8 Human; Coagulation Factor VIII Human; Coagulation factor VIII; Procoagulant component; Antihemophilic factor; AHF; F8; F8C; F8B; HEMA; FVIII; DXS1253E; F8 protein]
• Other_names
  [coagulation factor VIII isoform a; Coagulation factor VIII; coagulation factor VIII; antihemophilic factor; coagulation factor VIIIc; factor VIII F8B; coagulation factor VIII, procoagulant component; Antihemophilic factor; AHF; Procoagulant componentCleaved into the following 4 chains:Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain]
• Products_gene_name
  [F8]
• Other_gene_names
  [F8; F8; AHF; F8B; F8C; HEMA; FVIII; DXS1253E; F8C; AHF]
• Form
  The lyophilized protein 200IU/ml was lyophilized from a sterile solution containing 1.5% Glycine, 160mM Calcium chloride and 25mM NaCitrate and 25mM NaCl.Sterile Filtered White lyophilized (freeze-dried) powder.
• Storage_stability
  Lyophilized Factor-VIII although stable at room temperature for 1 week, should be stored desiccated between 2-8 degree C. Upon reconstitution Factor-VIII should be storedat 4 degree C.
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

• Gene target
  Coagulation   Factor   VIII  
• Gene symbol
  COX8A, G3BP1, MARCHF8
• Short name
  Coagulation Factor VIII
• Host
  Human Plasma
• Species
  Human, Humans
• Alternative name
  H. sapiens Coagulation Factor VIII

Gene info

• Identity
  HGNC:2294
• Gene
  COX8A
• Long gene name
  cytochrome c oxidase subunit 8A
• Synonyms gene
  • COX8
• Synonyms gene name
  • cytochrome c oxidase subunit VIII
  • cytochrome c oxidase subunit VIIIA (ubiquitous)
• Synonyms
  • COX8-2
  • COX8L
  • VIII-L
  • COX
  • VIII
• GenBank acession
  • J04823
• Locus
  11q13.1
• Discovery year
  1989-06-30
• Entrez gene record
  1351
• Pubmed identfication
  • 2543673
  • 2847943
  • 26685157
• RefSeq identity
  • NM_004074
• Classification
  • Mitochondrial complex IV: cytochrome c oxidase subunits
• VEGA ID
  OTTHUMG00000167785

Gene info

• Identity
  HGNC:30292
• Gene
  G3BP1
• Long gene name
  G3BP stress granule assembly factor 1
• Synonyms gene name
  • GTPase activating protein (SH3 domain) binding protein 1
• Synonyms
  • HDH-VIII
  • G3BP
• Synonyms name
  • Ras-GTPase-activating protein SH3-domain-binding protein
  • DNA helicase VIII
• GenBank acession
  • BC006997
• Locus
  5q33.1
• Discovery year
  2006-10-25
• Entrez gene record
  10146
• Pubmed identfication
  • 8649363
  • 9889278
  • 25229650
• RefSeq identity
  • NM_005754
• Classification
  • RNA binding motif containing
  • Endoribonucleases
• VEGA ID
  OTTHUMG00000130123

Gene info

• Identity
  HGNC:23356
• Gene
  MARCHF8
• Long gene name
  membrane associated ring-CH-type finger 8
• Synonyms gene
  • MIR
  • MARCH8
• Synonyms gene name
  • c-mir, cellular modulator of immune recognition
  • membrane-associated ring finger (C3HC4) 8
  • membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
• Synonyms
  • c-MIR
  • CMIR
  • MARCH-VIII
  • RNF178
• GenBank acession
  • AL833316
• Locus
  10q11.21-q11.22
• Discovery year
  2003-11-12
• Entrez gene record
  220972
• Pubmed identfication
  • 12582153
  • 14722266
• RefSeq identity
  • NM_145021
• Classification
  • Ring finger proteins
  • Membrane associated ring-CH-type fingers
• VEGA ID
  OTTHUMG00000019345

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