Human CellExp CD58/LFA-3; Fc Tag; human recombinant

Products_type

Active Protein
Products_short_name

[CD58/LFA-3]
Products_name_syn

[CD58; LFA3; Ag3]
Other_names

[Lymphocyte function-associated antigen 3; Lymphocyte function-associated antigen 3; lymphocyte function-associated antigen 3; CD58 molecule; Surface glycoprotein LFA-3; CD_antigen: CD58]
Products_gene_name

[CD58]
Products_gene_name_syn

[LFA-3]
Other_gene_names

[CD58; CD58; ag3; LFA3; LFA-3; LFA3; Ag3]
Purity

> 95%
Form

Lyophilized from 0.22 mum filtered solution in PBS; pH 7.4. Normally Trehalose is added as protectant before lyophilization.
Storage_stability

Store at -20 degree C for 12 months.Centrifuge the vial prior to opening.
Tested_application

SDS-PAGE, Functional Assay
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

CellExp CD58/LFA-3 Tag
Gene symbol

CD58, ITGAL, ITGB2, MIR1302-3, MIR509-3, MIR7-3, PIRC14, PIRC12
Short name

CellExp CD58/LFA-3; Fc Tag; recombinant
Technique

Recombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
Host

HEK 293 cellsSource: Human
Label

Fc Tag
Species

Human, Humans
Alternative name

H. sapiens CellExp CD58 molecule/LFA-3; fragment c detection labelled; H. sapiens Rec.
Alternative technique

rec
Alternative to gene target

CD58 molecule, ag3 and LFA-3 and LFA3, CD58 and IDBG-101394 and ENSG00000116815 and 965, protein binding, Cell surfaces, CD58 and IDBG-634482 and ENSBTAG00000040131 and 782186

Identity

HGNC:1688
Gene

CD58
Long gene name

CD58 molecule
Synonyms gene
- LFA3
Synonyms gene name
- CD58 antigen, (lymphocyte function-associated antigen 3)
GenBank acession
- BC005930
Locus

1p13.1
Discovery year

1989-04-06
Entrez gene record

965
Pubmed identfication
- 9510189
RefSeq identity
- NM_001779
Classification
- CD molecules
- Ig-like cell adhesion molecule family
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000022749

Identity

HGNC:6148
Gene

ITGAL
Long gene name

integrin subunit alpha L
Synonyms gene
- CD11A
Synonyms gene name
- integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
Synonyms
- LFA-1
- LFA1A
Synonyms name
- antigen CD11A (p180)
- lymphocyte function-associated antigen 1, alpha polypeptide
Locus

16p11.2
Discovery year

1986-01-01
Entrez gene record

3683
Pubmed identfication
- 3284962
Classification
- Integrin alpha subunits
- CD molecules
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000176964

Identity

HGNC:6155
Gene

ITGB2
Long gene name

integrin subunit beta 2
Synonyms gene
- CD18
- MFI7
Synonyms gene name
- integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
- integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
Synonyms
- LFA-1
- MAC-1
Synonyms name
- complement component 3 receptor 3 and 4 subunit
GenBank acession
- AK222505
Locus

21q22.3
Discovery year

1986-01-01
Entrez gene record

3689
RefSeq identity
- NM_000211
Classification
- Integrin beta subunits
- Complement system regulators and receptors
- CD molecules
VEGA ID

OTTHUMG00000090257
Locus Specific Databases
- ITGB2base: Mutation registry for Leukocyte adhesion deficiency I (LAD-I)
- LRG_76

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data