Human BMP receptor-1A, soluble

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Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

Gene target

BMP receptor-1A soluble
Gene symbol

IGHD1OR15-1A, UBP1, MTNR1A, IGKV2OR2-1, SCLT1, APH1A, HIF1A-AS1, HIF1A-AS2, MARK3, PPP1CA
Short name

BMP receptor-1A, soluble
Species

Human, Humans
Alternative name

H. sapiens BMP receptor-1A, soluble

Identity

HGNC:5805
Gene

IGKV2OR2-1
Long gene name

immunoglobulin kappa variable 2/OR2-1 (pseudogene)
Synonyms gene
- IGKV2OR2-1A
Synonyms gene name
- immunoglobulin kappa variable 2/OR2-1
- immunoglobulin kappa variable 2/OR2-1 pseudogene
Synonyms
- IGKV2/OR2-1
- IGKV2/OR2-1A
GenBank acession
- X05101
Locus

2q11.2
Discovery year

2000-04-18
Entrez gene record

28861
Pubmed identfication
- 8011175
Classification
- Immunoglobulin kappa (IGK) orphons
VEGA ID

OTTHUMG00000155332

Identity

HGNC:29509
Gene

APH1A
Long gene name

aph-1 homolog A, gamma-secretase subunit
Synonyms gene name
- anterior pharynx defective 1 homolog A (C. elegans)
- APH1A gamma secretase subunit
Synonyms
- APH-1A
- CGI-78
GenBank acession
- AF151835
Locus

1q21.2
Discovery year

2005-02-08
Entrez gene record

51107
Pubmed identfication
- 10810093
- 12110170
RefSeq identity
- NM_016022
VEGA ID

OTTHUMG00000012545

Identity

HGNC:9281
Gene

PPP1CA
Long gene name

protein phosphatase 1 catalytic subunit alpha
Synonyms gene
- PPP1A
Synonyms gene name
- protein phosphatase 1, catalytic subunit, alpha isoform
- protein phosphatase 1, catalytic subunit, alpha isozyme
Synonyms
- PP1A
- PP-1A
- PP1alpha
Locus

11q13.2
Discovery year

1989-10-11
Entrez gene record

5499
RefSeq identity
- NM_002708
Classification
- Protein phosphatase catalytic subunits
VEGA ID

OTTHUMG00000167671