HTT shRNA Plasmid (Human)

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Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Kit

Plasmid mini made and maxi DNA purification kits can be silica gel or anion exchange, endotoxin free and are used to produce pure plasmids that are small DNA molecules within a cell separated from chromosomal DNA and can replicate independently. They are most commonly found in bacteria as small circular, double-stranded DNA molecules; however, plasmids are sometimes present in archaea and eukaryotic organisms. In nature, plasmids often carry genes that may benefit the survival of the organism, for example antibiotic resistance. While the chromosomes are big and contain all the essential information for living, plasmids usually are very small and contain only additional information. Artificial plasmids are widely used as vectors in molecular cloning, serving to drive the replication of recombinant DNA sequences within host organisms.

Gene target

HTT shRNA
Gene symbol

HTT-AS, SLC6A4, HTT
Short name

HTT shRNA Plasmid ( )
Technique

plasmid, plasmids in 1
Species

Human, Humans
Alternative name

huntingtin short hairpin RNA Plasmid (H. sapiens)
Alternative technique

plasmids
Alternative to gene target

huntingtin, HD and IT15, HTT and IDBG-7852 and ENSG00000197386 and 3064, diazepam binding, nuclei, Htt and IDBG-156033 and ENSMUSG00000029104 and 15194, HTT and IDBG-643549 and ENSBTAG00000001506 and 615059

Identity

HGNC:37118
Gene

HTT-AS
Long gene name

HTT antisense RNA
Synonyms gene
- HTT-AS1
Synonyms gene name
- HTT antisense RNA 1 (non-protein coding)
- HTT antisense RNA 1
- HTT antisense RNA (head to head)
Synonyms
- HTTAS
Locus

4p16.3
Discovery year

2011-06-30
Entrez gene record

100750326
Pubmed identfication
- 21672921
- 23756188
RefSeq identity
- NR_045414
Classification
- Antisense RNAs
VEGA ID

OTTHUMG00000159915

Identity

HGNC:11050
Gene

SLC6A4
Long gene name

solute carrier family 6 member 4
Synonyms gene
- HTT
- OCD1
Synonyms gene name
- solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- 5-hydroxytryptamine (serotonin) transporter
- obsessive-compulsive disorder 1
- solute carrier family 6 (neurotransmitter transporter), member 4
Synonyms
- 5-HTT
- SERT1
Synonyms name
- serotonin transporter 1
GenBank acession
- L05568
Locus

17q11.2
Discovery year

1994-03-16
Entrez gene record

6532
Pubmed identfication
- 7681602
- 19806148
RefSeq identity
- NM_001045
Classification
- Solute carriers
VEGA ID

OTTHUMG00000132751