HIV Nef (90-100)

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Gene

The human immunodeficiency virus (HIV) is a lentivirus (a subgroup of retrovirus) that causes HIV infection and over time acquired immunodeficiency syndrome(AIDS). AIDS is a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. Without treatment, average survival time after infection with HIV is estimated to be 9 to 11 years, depending on the HIV subtype. Infection with HIV occurs by the transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk. Within these bodily fluids, HIV is present as both free virus particles and virus within infected immune cells. recombinant HIV 1 and 2 gag gene proteins p24, p17, p55 immunodominant epitopes and envelope glycoproteins, gp120 are used for production of diagnostic detection antibodies.

Gene target

HIV Nef 90-100
Gene symbol

SCARNA3, MIR100, TMED5, GFOD1, RMDN1, HLA-P, DLG4, PVT1, UBTF, HIVEP2
Short name

HIV Nef (90-100)
Alternative name

human immunodeficiency virus Nef (90-100)
Virus

hiv

Identity

HGNC:2903
Gene

DLG4
Long gene name

discs large MAGUK scaffold protein 4
Synonyms gene name
- discs, large homolog 4 (Drosophila)
- discs large homolog 4
Synonyms
- PSD-95
- PSD95
- SAP90
- SAP-90
GenBank acession
- U83192
Locus

17p13.1
Discovery year

1995-11-07
Entrez gene record

1742
Pubmed identfication
- 9286702
RefSeq identity
- NM_001365
Classification
- Membrane associated guanylate kinases
- PDZ domain containing
VEGA ID

OTTHUMG00000134327

Identity

HGNC:9709
Gene

PVT1
Long gene name

Pvt1 oncogene
Synonyms gene name
- pvt-1 (murine) oncogene homolog, MYC activator
- Pvt1 oncogene homolog (mouse)
- Pvt1 oncogene (non-protein coding)
Synonyms
Synonyms name
GenBank acession
- M31519
Locus

8q24.21
Discovery year

2001-06-22
Entrez gene record

5820
Pubmed identfication
- 17503467
- 23801869
RefSeq identity
- NR_003367
Classification
- Long non-coding RNAs with non-systematic symbols
- MicroRNA non-coding host genes
VEGA ID

OTTHUMG00000164871

Identity

HGNC:4921
Gene

HIVEP2
Long gene name

HIVEP zinc finger 2
Synonyms gene name
- human immunodeficiency virus type I enhancer-binding protein 2
- human immunodeficiency virus type I enhancer binding protein 2
Synonyms
- MBP-2
- HIV-EP2
- MIBP1
- ZAS2
- Schnurri-2
- ZNF40B
Synonyms name
- c-myc intron binding protein 1
GenBank acession
- M60119
Locus

6q24.2
Discovery year

1992-10-21
Entrez gene record

3097
Pubmed identfication
- 1733857
- 2022670
Classification
- Zinc fingers C2H2-type
VEGA ID

OTTHUMG00000015713