HIF1A shRNA Plasmid (Rat)

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Kit

Plasmid mini made and maxi DNA purification kits can be silica gel or anion exchange, endotoxin free and are used to produce pure plasmids that are small DNA molecules within a cell separated from chromosomal DNA and can replicate independently. They are most commonly found in bacteria as small circular, double-stranded DNA molecules; however, plasmids are sometimes present in archaea and eukaryotic organisms. In nature, plasmids often carry genes that may benefit the survival of the organism, for example antibiotic resistance. While the chromosomes are big and contain all the essential information for living, plasmids usually are very small and contain only additional information. Artificial plasmids are widely used as vectors in molecular cloning, serving to drive the replication of recombinant DNA sequences within host organisms.
About

Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
Latin name

Rattus norvegicus

Gene target

HIF1A shRNA
Gene symbol

HIF1A-AS3, HIF1A-AS1, HIF1A-AS2, HIF1A
Short name

HIF1A shRNA Plasmid ( )
Technique

plasmid, plasmids in 1
Host

Rat
Species

Rat, Rats
Alternative name

hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) short hairpin RNA Plasmid (Rat)
Alternative technique

plasmids
Alternative to gene target

hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor), bHLHe78 and HIF-1A and HIF-1alpha and HIF1 and HIF1-ALPHA and MOP1 and PASD8, HIF1A and IDBG-8510 and ENSG00000100644 and 3091, Hsp90 protein binding, nuclei, Hif1a and IDBG-148620 and ENSMUSG00000021109 and 15251, HIF1A and IDBG-646757 and ENSBTAG00000020935 and 281814

Identity

HGNC:4910
Gene

HIF1A
Long gene name

hypoxia inducible factor 1 subunit alpha
Synonyms gene name
- hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
Synonyms
- MOP1
- HIF-1alpha
- PASD8
- HIF1
- bHLHe78
Synonyms name
- PAS domain-containing protein 8”, “Class E basic helix-loop-helix protein 78”, “Member of PAS protein 1
GenBank acession
- U22431
Locus

14q23.2
Discovery year

1995-03-27
Entrez gene record

3091
Pubmed identfication
- 8786149
- 9079689
RefSeq identity
- NM_001530
Classification
- Basic helix-loop-helix proteins
VEGA ID

OTTHUMG00000140344