Heparin Binding EGF-like Growth Factor (HB-EGF, HBEGF, Diphtheria Toxin Receptor, DT-R, DTR)

• Catalog number
  MBS603983
• Price
  Please ask
• Size
  5x0.5 mg

• Products_type
  Antibody
• Products_short_name
  [Heparin Binding EGF-like Growth Factor]
• Products_name_syn
  [Anti -Heparin Binding EGF-like Growth Factor (HB-EGF, HBEGF, Diphtheria Toxin Receptor, DT-R, DTR)]
• Other_names
  [heparin-binding EGF-like growth factor; Proheparin-binding EGF-like growth factor; proheparin-binding EGF-like growth factor; OTTHUMP00000159876; heparin-binding epidermal growth factor; diphtheria toxin receptor (heparin-binding EGF-like growth factor); diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor); heparin-binding EGF-like growth factor; Diphtheria toxin receptor]
• Other_gene_names
  [HBEGF; HBEGF; DTR; DTS; DTSF; HEGFL; DTR; DTS; HEGFL]
• Clonality
  Monoclonal
• Clone
  [7H229]
• Reactivity
  Human
• Specificity
  Recognizes human Heparin Binding EGF-like Growth Factor (HB-EGF). Does not crossreact with recombinant human Amphiregulin, BTC, HRG-alpha, HRG-beta, EGF, TGF-alpha or recombinant mouse Epigen or Epiregulin.
• Purity
  Affinity Purified Purified by Protein G affinity chromatography.
• Form
  Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 1ml sterile PBS.
• Concentration
  ~0.5 mg/ml (after reconstitution)
• Storage_stability
  Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. 
• Tested_application
  ELISA (EL/EIA), Western Blot (WB), Neutralization
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Heparin   Binding   EGF-like   Growth   Factor   HB-EGF   HBEGF   Diphtheria   Receptor   DT-R   DTR  
• Gene symbol
  EGF, HBEGF, PPP1R42, HMHB1, KRT84, KRT85, KRT81, KRT82, KRT83, RRAS
• Short name
  Heparin Binding EGF-like Growth Factor (HB-EGF, HBEGF, Diphtheria Receptor, DT-R, DTR)
• Host
  Mouse
• Isotype
  IgG2a
• Alternative name
  Heparin Binding epidermal growth factor-like Growth Factor (HB-epidermal growth factor, HBEGF, Diphtheria Toxin Receptor, DT-R, DTR)
• Alternative to gene target
  epidermal growth factor, HOMG4 and URG, EGF and IDBG-34100 and ENSG00000138798 and 1950, transmembrane receptor protein tyrosine kinase activator activity, Extracellular, Egf and IDBG-193432 and ENSMUSG00000028017 and 13645

Gene info

• Identity
  HGNC:3229
• Gene
  EGF
• Long gene name
  epidermal growth factor
• Synonyms gene name
  • epidermal growth factor (beta-urogastrone)
• Synonyms name
  • Pro-epidermal growth factor
• GenBank acession
  • X04571
• Locus
  4q25
• Discovery year
  2001-06-22
• Entrez gene record
  1950
• VEGA ID
  OTTHUMG00000132044

Gene info

• Identity
  HGNC:3059
• Gene
  HBEGF
• Long gene name
  heparin binding EGF like growth factor
• Synonyms gene
  • HEGFL
  • DTS
  • DTR
• Synonyms gene name
  • diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor)
  • heparin-binding EGF-like growth factor
• Synonyms name
  • Diphtheria toxin receptor (heparin-binding EGF-like growth factor)
  • heparin-binding epidermal growth factor
• Locus
  5q31.3
• Discovery year
  2001-06-22
• Entrez gene record
  1839
• Pubmed identfication
  • 7590736
  • 12163414
• RefSeq identity
  • NM_001945
• VEGA ID
  OTTHUMG00000129496

Gene info

• Identity
  HGNC:33732
• Gene
  PPP1R42
• Long gene name
  protein phosphatase 1 regulatory subunit 42
• Synonyms gene
  • LRRC67
• Synonyms gene name
  • leucine rich repeat containing 67
  • protein phosphatase 1, regulatory subunit 42
• Synonyms
  • dtr
  • TLLR
• Synonyms name
  • testis leucine-rich repeat
• GenBank acession
  • BC055413
• Locus
  8q13.1
• Discovery year
  2008-06-11
• Entrez gene record
  286187
• RefSeq identity
  • NM_001013626
• Classification
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000164745

Gene info

• Identity
  HGNC:29677
• Gene
  HMHB1
• Long gene name
  histocompatibility minor HB-1
• Synonyms
  • HB-1
  • HB-1Y
• GenBank acession
  • AF103884
• Locus
  5q31.3
• Discovery year
  2006-07-20
• Entrez gene record
  57824
• Pubmed identfication
  • 9892612
• RefSeq identity
  • NM_021182
• Classification
  • Minor histocompatibility antigens
• VEGA ID
  OTTHUMG00000163173

Gene info

• Identity
  HGNC:6461
• Gene
  KRT84
• Long gene name
  keratin 84
• Synonyms gene
  • KRTHB4
• Synonyms gene name
  • keratin, hair, basic, 4
  • keratin 84, type II
• Synonyms
  • Hb-4
• Synonyms name
  • hard keratin type II 4
• GenBank acession
  • Y19209
• Locus
  12q13.13
• Discovery year
  1998-04-21
• Entrez gene record
  3890
• Pubmed identfication
  • 2431943
  • 16831889
• RefSeq identity
  • NM_033045
• Classification
  • Keratins, type II
• VEGA ID
  OTTHUMG00000169634

Gene info

• Identity
  HGNC:6462
• Gene
  KRT85
• Long gene name
  keratin 85
• Synonyms gene
  • KRTHB5
• Synonyms gene name
  • keratin, hair, basic, 5
  • keratin 85, type II
• Synonyms
  • Hb-5
• Synonyms name
  • hard keratin type II
• GenBank acession
  • X99140
• Locus
  12q13.13
• Discovery year
  1998-04-21
• Entrez gene record
  3891
• Pubmed identfication
  • 9084137
  • 16831889
• RefSeq identity
  • NM_002283
• Classification
  • Keratins, type II
• VEGA ID
  OTTHUMG00000169633

Gene info

• Identity
  HGNC:6458
• Gene
  KRT81
• Long gene name
  keratin 81
• Synonyms gene
  • KRTHB1
• Synonyms gene name
  • keratin, hair, basic, 1
  • keratin 81, type II
• Synonyms
  • Hb-1
• Synonyms name
  • hard keratin type II 1
• GenBank acession
  • X81420
• Locus
  12q13.13
• Discovery year
  1998-04-21
• Entrez gene record
  3887
• Pubmed identfication
  • 7556444
  • 16831889
• RefSeq identity
  • NM_002281
• Classification
  • Keratins, type II
• VEGA ID
  OTTHUMG00000167574

Gene info

• Identity
  HGNC:6459
• Gene
  KRT82
• Long gene name
  keratin 82
• Synonyms gene
  • KRTHB2
• Synonyms gene name
  • keratin, hair, basic, 2
  • keratin 82, type II
• Synonyms
  • Hb-2
• Synonyms name
  • hard keratin type II 2
• GenBank acession
  • Y19207
• Locus
  12q13.13
• Discovery year
  1998-04-21
• Entrez gene record
  3888
• Pubmed identfication
  • 2431943
  • 16831889
• RefSeq identity
  • NM_033033
• Classification
  • Keratins, type II
• VEGA ID
  OTTHUMG00000169636

Gene info

• Identity
  HGNC:6460
• Gene
  KRT83
• Long gene name
  keratin 83
• Synonyms gene
  • KRTHB3
• Synonyms gene name
  • keratin, hair, basic, 3
  • keratin 83, type II
• Synonyms
  • Hb-3
• Synonyms name
  • hard keratin type II
• GenBank acession
  • X99141
• Locus
  12q13.13
• Discovery year
  1998-04-21
• Entrez gene record
  3889
• Pubmed identfication
  • 9084137
  • 16831889
• RefSeq identity
  • NM_002282
• Classification
  • Keratins, type II
• VEGA ID
  OTTHUMG00000169632
• Locus Specific Databases
  • LRG_1302

Gene info

• Identity
  HGNC:10447
• Gene
  RRAS
• Long gene name
  RAS related
• Synonyms gene name
  • related RAS viral (r-ras) oncogene homolog
• Synonyms
  • R-Ras
• Synonyms name
  • Oncogene RRAS
• Locus
  19q13.33
• Discovery year
  2001-06-22
• Entrez gene record
  6237
• Pubmed identfication
  • 3098437
• RefSeq identity
  • NM_006270
• Classification
  • RAS type GTPase family
• VEGA ID
  OTTHUMG00000183247

MeSH Data

• Name
  Radioimmunosorbent Test
• Concept
  Scope note: Radioimmunoassay of proteins using antibody coupled to an immunosorbent.
• Tree numbers
  • E05.478.566.380.830
  • E05.478.566.639.830
  • E05.601.470.380.830
  • E05.601.470.639.830
• Qualifiers
  ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data

Similar products