GRP94 / HSP90B1 (Endoplasmic Reticulum Marker) Rat Monoclonal Antibody

• Catalog number
  MBS439801
• Price
  Please ask
• Size
  0.1 mg (With BSA & Azide at 0.2mg/mL)

• Products_type
  Antibody
• Products_short_name
  [GRP94 / HSP90B1]
• Products_name_syn
  [Glucose Regulated Protein 94; 94kDa glucose-regulated protein, Endoplasmin, Endothelial cell (HBMEC) glycoprotein (ECGP), Heat shock protein 90kDa beta member 1 (HSP90B1), Stress inducible tumor rejection antigen GP96, TRA1, Tumor rejection antigen-1 (gp96)]
• Other_names
  [endoplasmin; Endoplasmin; endoplasmin; heat shock protein 90 beta family member 1; 94 kDa glucose-regulated protein; GRP-94; Heat shock protein 90 kDa beta member 1; Tumor rejection antigen 1; gp96 homolog]
• Products_gene_name
  [HSP90B1]
• Other_gene_names
  [HSP90B1; HSP90B1; ECGP; GP96; TRA1; GRP94; HEL35; HEL-S-125m; GRP94; TRA1; GRP-94]
• Clonality
  Monoclonal
• Clone
  [HSP90B1/1192]
• Reactivity
  Human. Shows broad species reactivity
• Specificity
  Recognizes a protein of 94kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96). Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90). This MAb is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grp s are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer.
• Form
  200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml.
• Storage_stability
  Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Tested_application
  Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin
• Properties
  If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• Latin name
  Rattus norvegicus
• French translation
  anticorps

• Gene target
  GRP94   HSP90B1   Endoplasmic   Reticulum   Monoclonal  
• Gene symbol
  HSP90B1
• Short name
  GRP94 / HSP90B1 (Endoplasmic Reticulum ) Monoclonal Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for, Component cell markers and DNA bp. markers are genetic markers er genes or DNA sequences with a known location on a chromosome that can be used to identify individuals or species. Protein markers in kDA. Monoclonals or monoclonal antibodies
• Host
  Rat
• Isotype
  IgG2a, kappa
• Species
  Rat, Rats
• Alternative name
  GRP94 / heat shock protein 90kDa b (Grp94), member 1 (Endoplasmic Reticulum detection labelled) Rat monoclonal (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  heat shock protein 90kDa beta (Grp94), member 1, ECGP and GP96 and GRP94 and HEL-S-125m and HEL35 and TRA1, HSP90B1 and IDBG-54092 and ENSG00000166598 and 100500842,7184, unfolded protein binding, nuclei, Hsp90b1 and IDBG-182078 and ENSMUSG00000020048 and 22027, HSP90B1 and IDBG-637404 and ENSBTAG00000003362 and 282646

Gene info

• Identity
  HGNC:12028
• Gene
  HSP90B1
• Long gene name
  heat shock protein 90 beta family member 1
• Synonyms gene
  • TRA1
• Synonyms gene name
  • tumor rejection antigen (gp96) 1
  • heat shock protein 90kDa beta (Grp94), member 1
• Synonyms
  • GP96
  • GRP94
• Synonyms name
  • endoplasmin
• GenBank acession
  • AY040226
• Locus
  12q23.3
• Discovery year
  1991-07-03
• Entrez gene record
  7184
• Pubmed identfication
  • 16269234
• RefSeq identity
  • NM_003299
• Classification
  • Heat shock 90kDa proteins
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000170118

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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