Granzyme B, Recombinant, Mouse (C11, Cathespin G Like 1, CCP1, CGL1, CSPB, CTLA1,CTSGL1, Cytotoxic serine protease B, Cytotoxic T Lymphocyte Cytotoxic T lymphocyte proteinase 2, EC 3.4.21.79, Fragmentin 2, Granzyme 2, GRB, GZMB, HLP, Human lymphocyte prot

Catalog number

MBS637182
Price

Please ask
Size

0.01 mg

Products_type

Active Protein
Products_short_name

[Granzyme B]
Products_name_syn

[Granzyme B, Recombinant, Mouse (C11, Cathespin G Like 1, CCP1, CGL1, CSPB, CTLA1,CTSGL1, Cytotoxic serine protease B, Cytotoxic T Lymphocyte Cytotoxic T lymphocyte proteinase 2, EC 3.4.21.79, Fragmentin 2, Granzyme 2, GRB, GZMB, HLP, Human lymphocyte prot]
Other_names

[granzyme B; Granzyme B; granzyme B; C11; CTLA-1; fragmentin 2; fragmentin-2; cathepsin G-like 1; human lymphocyte protein; T-cell serine protease 1-3E; cytotoxic serine protease B; cytotoxic T-lymphocyte proteinase 2; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); C11; CTLA-1; Cathepsin G-like 1; CTSGL1; Cytotoxic T-lymphocyte proteinase 2; Lymphocyte protease; Fragmentin-2; Granzyme-2; Human lymphocyte protein; HLP; SECT; T-cell serine protease 1-3E]
Other_gene_names

[GZMB; GZMB; HLP; CCPI; CGL1; CSPB; SECT; CGL-1; CSP-B; CTLA1; CTSGL1; CGL1; CSPB; CTLA1; GRB; CTSGL1; Lymphocyte protease; HLP]
Purity

Highly Purified98% by SDS-PAGE and HPLC analyses.
Form

Supplied as a lyophilized powder.
Storage_stability

Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile buffer, aliquot and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Test

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name

Mus musculus
Source

Recombinants or rec. proteins
Group

recombinants
Description

Serine protease, D- or L-serine arginine rich enzyme of serine threonine kinase with serine that is encoded by the codons UCU, UCC, UCA, UCG, AGU and AGC is an ɑ-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH+ 3 form under biological conditions), a carboxyl group. It is non-essential in humans, meaning the body can synthesize it.

Gene target

Granzyme C11 Cathespin Like CCP1 CGL1 CSPB CTLA1 CTSGL1 Cytotoxic serine protease Cytotoxic Lymphocyte Cytotoxic lymphocyte proteinase Fragmentin Granzyme GRB GZMB HLP lymphocyte prot
Gene symbol

GZMB, POLR3K, AGTPBP1, CCDC115, ERVK3-4, HAP1, SKIV2L, GZMH, AKR1C4
Short name

Granzyme B, Recombinant, Mouse (C11, Cathespin G Like 1, CCP1, CGL1, CSPB, CTLA1 CTSGL1, Cytotoxic serine protease B, Cytotoxic T Lymphocyte Cytotoxic T lymphocyte proteinase 2, EC 3 4 21 79, Fragmentin 2, Granzyme 2, GRB, GZMB, HLP, lymphocyte prot
Technique

Recombinant, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Host

Baculovirus infected High-5 cells
Species

Human, Humans, Mouses
Alternative name

Granzyme B, Rec., Mouse (C11, Cathespin G Like 1, CCP1, CGL1, CSPB, CTLA1,CTSGL1, Cytotoxic serine protease B, Cytotoxic T Lymphocyte Cytotoxic T lymphocyte proteinase 2, EC 3.4.21.79, Fragmentin 2, Granzyme 2, GRB, granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1), HLP, H. sapiens lymphocyte prot
Alternative technique

rec, murine
Alternative to gene target

granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1), CCPI and CGL-1 and CGL1 and CSP-B and CSPB and CTLA1 and CTSGL1 and HLP and SECT, GZMB and IDBG-4054 and ENSG00000100453 and 3002, serine-type peptidase activity, nuclei, BT.19365 and IDBG-632083 and ENSBTAG00000010057 and 508646
Tissue

lymphocyte

Gene info

Identity

HGNC:4709
Gene

GZMB
Long gene name

granzyme B
Synonyms gene
- CTLA1
- CSPB
Synonyms gene name
- granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
Synonyms
- CCPI
- CGL-1
- CSP-B
- CGL1
- CTSGL1
- HLP
- SECT
Synonyms name
GenBank acession
- BC030195
Locus

14q12
Discovery year

1989-05-12
Entrez gene record

3002
Pubmed identfication
- 2323780
RefSeq identity
- NM_004131
Classification
- Granule associated serine proteases of immune defence
VEGA ID

OTTHUMG00000029369

Gene info

Identity

HGNC:14121
Gene

POLR3K
Long gene name

RNA polymerase III subunit K
Synonyms gene name
- polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
Synonyms
- RPC11
- C11
GenBank acession
- AF051316
Locus

16p13.3
Discovery year

2000-12-21
Entrez gene record

51728
Pubmed identfication
- 9869639
- 10079944
RefSeq identity
- NM_016310
Classification
- RNA polymerase subunits
VEGA ID

OTTHUMG00000060722

Gene info

Identity

HGNC:17258
Gene

AGTPBP1
Long gene name

ATP/GTP binding carboxypeptidase 1
Synonyms gene name
- ATP/GTP binding protein 1
Synonyms
- KIAA1035
- Nna1
- CCP1
Synonyms name
GenBank acession
- AB028958
Locus

9q21.33
Discovery year

2002-03-27
Entrez gene record

23287
Pubmed identfication
- 11083920
RefSeq identity
- NM_015239
Classification
- Armadillo like helical domain containing
- M14 carboxypeptidases
VEGA ID

OTTHUMG00000020124

Gene info

Identity

HGNC:28178
Gene

CCDC115
Long gene name

coiled-coil domain containing 115
Synonyms
- MGC12981
- FLJ30131
- ccp1
GenBank acession
- AK054693
Locus

2q21.1
Discovery year

2006-07-03
Entrez gene record

84317
Pubmed identfication
- 21118521
- 26833332
RefSeq identity
- NM_032357
VEGA ID

OTTHUMG00000131631

Gene info

Identity

HGNC:39109
Gene

ERVK3-4
Long gene name

endogenous retrovirus group K3 member 4
Synonyms gene name
- endogenous retrovirus group K3, member 4
Synonyms
- HML6-c11
GenBank acession
- FR714894
Locus

11p15.4
Discovery year

2011-05-05
Pubmed identfication
- 18077721
- 21542922

Gene info

Identity

HGNC:4812
Gene

HAP1
Long gene name

huntingtin associated protein 1
Synonyms gene
- HAP2
Synonyms gene name
- huntingtin-associated protein 1
Synonyms
- HLP
- hHLP1
- HIP5
Synonyms name
- neuroan 1
GenBank acession
- AF040723
Locus

17q21.2
Discovery year

1999-04-28
Entrez gene record

9001
Pubmed identfication
- 7477378
- 9668110
RefSeq identity
- NM_003949
VEGA ID

OTTHUMG00000133498

Gene info

Identity

HGNC:10898
Gene

SKIV2L
Long gene name

Ski2 like RNA helicase
Synonyms gene
- SKIV2
Synonyms gene name
- superkiller viralicidic activity 2 (S. cerevisiae homolog)-like
- superkiller viralicidic activity 2-like (S. cerevisiae)
- SKI2 homolog, superkiller viralicidic activity 2-like
Synonyms
- HLP
- DDX13
- SKI2W
- 170A
- SKIV2L1
Locus

6p21.33
Discovery year

1995-07-06
Entrez gene record

6499
Pubmed identfication
- 7759100
- 9799600
RefSeq identity
- NM_006929
Classification
- RNA helicases
- Ski2 like RNA helicases
VEGA ID

OTTHUMG00000031146

Gene info

Identity

HGNC:4710
Gene

GZMH
Long gene name

granzyme H
Synonyms gene
- CTSGL2
Synonyms gene name
- granzyme H (cathepsin G-like 2, protein h-CCPX)
Synonyms
- CGL-2
- CCP-X
- CTLA1
- CSP-C
Synonyms name
- cathepsin G-like 2, protein h-CCPX
GenBank acession
- M72150
Locus

14q12
Discovery year

1990-04-09
Entrez gene record

2999
Pubmed identfication
- 2049336
RefSeq identity
- NM_033423
Classification
- Granule associated serine proteases of immune defence
VEGA ID

OTTHUMG00000140185

Gene info

Identity

HGNC:387
Gene

AKR1C4
Long gene name

aldo-keto reductase family 1 member C4
Synonyms gene
- CHDR
Synonyms gene name
- aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)
Synonyms
- DD4
- HAKRA
- C11
- 3-alpha-HSD
- CDR
- MGC22581
Synonyms name
GenBank acession
- M33375
Locus

10p15.1
Discovery year

1993-08-26
Entrez gene record

1109
Pubmed identfication
- 7789999
RefSeq identity
- NM_001818
Classification
- Aldo-keto reductases
VEGA ID

OTTHUMG00000017591

MeSH Data

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Granzyme B, Recombinant, Mouse (C11, Cathespin G Like 1, CCP1, CGL1, CSPB, CTLA1,CTSGL1, Cytotoxic serine protease B, Cytotoxic T Lymphocyte Cytotoxic T lymphocyte proteinase 2, EC 3.4.21.79, Fragmentin 2, Granzyme 2, GRB, GZMB, HLP, Human lymphocyte prot

Gene info

Gene info

Gene info

Gene info

Gene info

Gene info

Gene info

Gene info

Gene info

MeSH Data

Product images

Similar products