gp100/ Melanosome/ PMEL17/ SILV

• Catalog number
  MBS438452
• Price
  Please ask
• Size
  5x0.1 mg (With BSA & Azide at 0.2mg/mL)

• Products_type
  Antibody
• Products_short_name
  [gp100]
• Products_name_syn
  [95kDa melanocyte-specific secreted glycoprotein; M-beta; Melanocyte lineage specific antigen GP100; Melanocyte protein Pmel 17; Melanoma associated ME20 antigen; Melanosomal matrix protein17; p100; p26; PMEL17; Premelanosome protein; Secreted melanoma-associated ME20 antigen; SILV; Silver homolog]
• Other_names
  [melanocyte protein PMEL isoform 2; Melanocyte protein PMEL; melanocyte protein PMEL; melanocyte protein mel 17; silver, mouse, homolog of; melanocyte protein Pmel 17; melanosomal matrix protein17; silver locus protein homolog; melanoma-associated ME20 antigen; melanocytes lineage-specific antigen GP100; premelanosome protein; ME20-M; ME20M; Melanocyte protein Pmel 17; Melanocytes lineage-specific antigen GP100; Melanoma-associated ME20 antigen; P1; P100; Premelanosome protein; Silver locus protein homologCleaved into the following 2 chains:M-alphaAlternative name(s):95 kDa melanocyte-specific secreted glycoprotein; P26; Secreted melanoma-associated ME20 antigen; ME20-S; ME20S]
• Products_gene_name
  [SILV]
• Other_gene_names
  [PMEL; PMEL; P1; SI; SIL; ME20; P100; SILV; ME20M; gp100; ME20-M; PMEL17; D12S53E; D12S53E; PMEL17; SILV; ME20M; ME20-S; ME20S]
• Clonality
  Monoclonal
• Clone
  [NKI-beteb]
• Reactivity
  Human, Horse.Does not react with rat, Others-not tested.
• Specificity
  By immunohistochemistry, it specifically recognizes a protein in melanocytes and melanomas. This MAb reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.This Mab labels formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
• Form
  200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Storage_stability
  Store at 2 to 8 degree C. Antibody is stable for 24 months.
• Tested_application
  ELISA (EIA), Flow Cytometry(FC/FACS, Immunofluorescence (IF), Immunohistology(IH)

• Gene target
  gp100   Melanosome   PMEL17   SILV  
• Gene symbol
  PMEL
• Short name
  gp100/ Melanosome/ PMEL17/ SILV
• Host
  Mouse
• Isotype
  IgG2b, kappa
• Alternative name
  gp100/ Melanosome/ PMEL17/ SILV

Gene info

• Identity
  HGNC:10880
• Gene
  PMEL
• Long gene name
  premelanosome protein
• Synonyms gene
  • SIL
  • SILV
• Synonyms gene name
  • silver (mouse homolog) like
  • silver homolog (mouse)
• Synonyms
  • D12S53E
  • SI
  • Pmel17
  • gp100
  • HMB-45
  • ME20
• GenBank acession
  • AK092881
• Locus
  12q13.2
• Discovery year
  1997-06-24
• Entrez gene record
  6490
• Pubmed identfication
  • 8739560
• RefSeq identity
  • NM_006928
• VEGA ID
  OTTHUMG00000170573

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