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Products_type
Antibody
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Products_short_name
[Gonadotropin-releasing Hormone Receptor]
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Products_name_syn
[Anti -Gonadotropin-releasing Hormone Receptor (GnRH Receptor, GNRHR, GnRH-R, GNRHR1, GRHR, Luteinizing Hormone Releasing Hormone Receptor, LHRHR, Leutinizing-releasing Hormone Receptor, LRHR, Luliberin Receptor, Type I GnRH Receptor)]
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Other_names
[gonadotropin releasing hormone receptor; Gonadotropin-releasing hormone receptor; gonadotropin-releasing hormone receptor; gnRH-R; gnRH receptor; OTTHUMP00000159637; OTTHUMP00000218970; luliberin receptor; type I GnRH receptor; leutinizing-releasing hormone receptor; leutinizing hormone releasing horomone receptor; gonadotropin-releasing hormone (type 1) receptor 1; gonadotropin-releasing hormone receptor]
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Other_gene_names
[GNRHR; GNRHR; GRHR; LRHR; LHRHR; GNRHR1; GRHR]
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Clonality
Monoclonal
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Clone
[F1G4]
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Reactivity
Human
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Specificity
Recognizes the human Gonadotropin-releasing Hormone Receptor in the anterior pituitary.
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Purity
Purified Purified
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Form
Supplied as a liquid in PBS, 0.05% sodium azide.
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Storage_stability
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested_application
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Gel Shift Assay (GS/EMSA)
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Description
Hormone releasing factors and releasing hormones are signaling molecules produced by glands in multicellular organisms. The glands that secrete Luteinizing hormones LHRG and LH, FSH comprise the endocrine signaling system. The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signaling) or nearby cells (paracrine signaling). Human recombinant LHRG and GHRH are produced in E. coli or in yeast cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
