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Products_type
Antibody
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Products_short_name
[POLL / DNA Polymerase Lambda]
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Products_name_syn
[Anti-POLL / DNA Polymerase Lambda Antibody (C-Terminus) IHC-plus; POLL; DNA polymerase beta-2; DNA polymerase beta-N; DNA polymerase lambda; DNA polymerase kappa; Pol beta2; BETAN; Pol Lambda; POLKAPPA; Human POLL; DNA Polymerase Lambda]
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Other_names
[DNA polymerase lambda isoform a; DNA polymerase lambda; DNA polymerase lambda; DNA polymerase kappa; DNA polymerase beta-2; DNA polymerase beta-N; polymerase (DNA directed), lambda; DNA polymerase beta-2; Pol beta2; DNA polymerase kappa]
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Products_gene_name
[POLL]
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Other_gene_names
[POLL; POLL; BETAN; POLKAPPA; Pol Lambda; Pol beta2]
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Clonality
Polyclonal
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Reactivity
Bat, Gibbon, Bovine, Gorilla, Hamster, Human, Monkey, Mouse, Orangutan, Pig, Rabbit, Rat Predicted Reactivity: Dog, Chicken (at least 90% immunogen sequence identity)
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Specificity
Human POLL. It has been brought to our attention that this product may crossreact with Pol beta (NP_002681), an evolutionarilly related polymerase with a predicted size of 39 kDa. The overall % of identity is not very high (about 32% in the core) but considering only the peptide that we used as immunogen the two share the sequence YREP**R** at the C-terminus. Further the protein structures appear to be very similar in this region.
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Purity
Immunoaffinity Purified
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Form
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
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Concentration
0.5 mg/ml
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Storage_stability
Store at -20 degree C. Minimize freezing and thawing.
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Tested_application
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
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Latin name
Capra aegagrus hircus
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Group
Polyclonals and antibodies
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About
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
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Gene target
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Gene symbol
POLL, PRKDC, HLA-DOA
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Short name
Goat Polyclonal POLL / DNA Polymerase Lambda
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Technique
Polyclonal, Goat, dna, goats, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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Host
Goat, The goat polyclonal antibodies are directed against human genes or rabbit or mouse IgGs (H +L) chain primary antibodies and conjugated for detection. It are very good secondary antibodies that are affinity purified and have a good affinity themselves too. Often KLH is coupled to the antigen so anti KLH can be present in the vial.
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Species
Human, Goats, Humans
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Alternative name
caprine polyclonal to H. sapiens polymerase (Desoxyribonucleic acid directed), lambda / Desoxyribonucleic acid polymerizing enzyme Lambda
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Alternative technique
polyclonals, caprine
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Alternative to gene target
polymerase (DNA directed), lambda, POLL and IDBG-87156 and ENSG00000166169 and 27343, metal ion binding, nuclei, Poll and IDBG-170875 and ENSMUSG00000025218 and 56626, POLL and IDBG-638887 and ENSBTAG00000003576 and 522307
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