Goat Polyclonal to Human CFB / Complement Factor B

• Catalog number
  MBS243747
• Price
  Please ask
• Size
  1 mL

• Products_type
  Antibody
• Products_short_name
  [CFB / Complement Factor B]
• Products_name_syn
  [Anti-CFB / Complement Factor B Antibody IHC-plus; CFB; AHUS4; B-factor; properdin; C3/C5 convertase; CFAB; C3 proaccelerator; C3 proactivator; Complement factor B; Complement protein Factor B; Glycine-rich beta-glycoprotein; GBG; Factor B; FB; Glycine-rich beta glycoprotein; PBF2; BF; BFD; FBI12; Human CFB; Complement Factor B]
• Other_names
  [complement factor B preproprotein; Complement factor B; complement factor B; C3 proactivator; C3/C5 convertase; C3 proaccelerator; properdin factor B; B-factor, properdin; glycine-rich beta glycoprotein; glycine-rich beta-glycoprotein; complement factor B; C3/C5 convertase; Glycine-rich beta glycoprotein; GBG; PBF2; Properdin factor BCleaved into the following 2 chains:Complement factor B Ba fragment; Complement factor B Bb fragment]
• Products_gene_name
  [CFB]
• Other_gene_names
  [CFB; CFB; BF; FB; BFD; GBG; CFAB; CFBD; PBF2; AHUS4; FBI12; H2-Bf; ARMD14; BF; BFD; GBG]
• Clonality
  Polyclonal
• Reactivity
  Human
• Specificity
  Human CFB / Factor B. In immunoelectrophoresis against human EDTA plasma a single precipitin line is obtained in the beta-2 region. The antiserum does not react with any other protein component of human serum or plasma. Cross-reactivity The antiserum does not cross-react with any other human plasma proteins as tested in gel- diffusion techniques. Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins, since homologous proteins of different species frequently share antigenic determinants. Cross-reactivity of this antiserum has not been tested in detail, however in double radial immunodiffusion a weak reaction with mouse has been observed.
• Purity
  Immunoaffinity Absorbed
• Form
  Lyophilized antiserum
• Storage_stability
  Store lyophilized at 4 degree C. Once reconstituted, aliquot and store at -20 degree C. Avoid freeze/thaw cycles. Store undiluted.
• Tested_application
  Immunohistochemistry (IHC - Paraffin), Immunodiffusion
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
• Latin name
  Capra aegagrus hircus
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

• Gene target
  CFB   Complement   Factor  
• Gene symbol
  CFB
• Short name
  Goat Polyclonal CFB / Complement Factor B
• Technique
  Polyclonal, Goat, goats, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Host
  Goat, The goat polyclonal antibodies are directed against human genes or rabbit or mouse IgGs (H +L) chain primary antibodies and conjugated for detection. It are very good secondary antibodies that are affinity purified and have a good affinity themselves too. Often KLH is coupled to the antigen so anti KLH can be present in the vial.
• Species
  Human, Goats, Humans
• Alternative name
  caprine polyclonal to H. sapiens Complement factor B Ba fragment; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B / Complement Factor B
• Alternative technique
  polyclonals, caprine
• Alternative to gene target
  Complement factor B Ba fragment; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B, CFB and IDBG-406598 and ENSG00000244255 and, serine-type endopeptidase activity, multiple

Gene info

• Identity
  HGNC:1037
• Gene
  CFB
• Long gene name
  complement factor B
• Synonyms gene
  • BFD
  • BF
• Synonyms gene name
  • B-factor, properdin
• Synonyms
  • H2-Bf
• GenBank acession
  • L15702
• Locus
  6p21.33
• Discovery year
  1986-01-01
• Entrez gene record
  629
• RefSeq identity
  • NM_001710
• Classification
  • Complement system activation components
  • Sushi domain containing
• VEGA ID
  OTTHUMG00000031198
• Locus Specific Databases
  • LRG_136

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